Package: nlmixr2 2.1.2

Matthew Fidler

nlmixr2: Nonlinear Mixed Effects Models in Population PK/PD

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Authors:Matthew Fidler [aut, cre], Yuan Xiong [ctb], Rik Schoemaker [ctb], Justin Wilkins [ctb], Wenping Wang [ctb], Mirjam Trame [ctb], Huijuan Xu [ctb], John Harrold [ctb], Bill Denney [ctb], Theodoros Papathanasiou [ctb], Teun Post [ctb], Richard Hooijmaijers [ctb]

nlmixr2_2.1.2.tar.gz
nlmixr2_2.1.2.zip(r-4.5)nlmixr2_2.1.2.zip(r-4.4)nlmixr2_2.1.2.zip(r-4.3)
nlmixr2_2.1.2.tgz(r-4.4-any)nlmixr2_2.1.2.tgz(r-4.3-any)
nlmixr2_2.1.2.tar.gz(r-4.5-noble)nlmixr2_2.1.2.tar.gz(r-4.4-noble)
nlmixr2_2.1.2.tgz(r-4.4-emscripten)nlmixr2_2.1.2.tgz(r-4.3-emscripten)
nlmixr2.pdf |nlmixr2.html✨
nlmixr2/json (API)
NEWS

# Install 'nlmixr2' in R:
install.packages('nlmixr2', repos = c('https://nlmixr2.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/nlmixr2/nlmixr2/issues

On CRAN:

95 exports 37 stars 3.43 score 146 dependencies 2 dependents 1.2k downloads

Last updated 9 days agofrom:95abbab7d9

Exports:.nlmixrNlmeFun%>%ACFadd.dosingadd.samplingaddCwresaddNpdeaddTableaugPredbobyqaControlbootplotbootstrapFitcovarSearchAutoetetExpandeventTableexpitfixed.effectsfixeffoceiControlgeom_amtgeom_censgetDatagetVarCovgroupedDatainiini<-lbfgsb3cControllogitlotrimodelmodel<-n1qn1ControlnewuoaControlnlmControlnlmenlmeControlnlminbControlnlmixrnlmixr2nlmixr2AllEstnlmixr2CheckInstallnlmixr2NlmeControlnlsControloptimControlpdBlockedpdCompSymmpdConstructpdDiagpdFactorpdIdentpdLogCholpdMatpdMatrixpdNaturalpdSymmpreconditionFitprobitprobitInvrandom.effectsranefreStructrxCatrxCleanrxControlrxDerivedrxFunrxodeRxODErxode2rxParamrxParamsrxSetPipingAutorxSolvesaemControlsetOfvstat_amtstat_censtableControltraceplotuobyqaControlvarCombvarConstPowerVarCorrvarExpvarFixedvarFuncvarIdentvarPowervarWeightsvpcCensvpcCensTadvpcPlotvpcPlotTadvpcSim

Dependencies:askpassassertthatbackportsbase64encBHbinombitbit64bitopsbootbslibcachemcellrangercheckmateclassclassIntclicliprclustercolorspacecommonmarkcpp11crayoncurldata.tableDerivDescToolsdigestdparserdplyre1071evaluateExactexpmfansifarverfastmapfontawesomeforeignFormulafsgenericsggplot2ggtextgldgluegridExtragridtextgtablehighrHmischmshtmlTablehtmltoolshtmlwidgetshttrinlineisobandjpegjquerylibjsonliteKernSmoothknitrlabelinglatticelazyevallbfgsb3clifecyclelmomlotrimagrittrmarkdownMASSMatrixmemoisemgcvmimeminpack.lmminqamunsellmvtnormn1qn1nlmenlmixr2datanlmixr2estnlmixr2extranlmixr2plotnnetnumDerivopensslpanderpillarpkgconfigpngPreciseSumsprettyunitsprogressproxypurrrqsR6RApiSerializerappdirsRColorBrewerRcppRcppArmadilloRcppEigenRcppParallelRCurlreadrreadxlrematchrexrlangrmarkdownrootSolverpartrstudioapirxode2rxode2llsassscalessitmoStanHeadersstringfishstringistringrsurvivalsymenginesystibbletidyrtidyselecttinytextzdbutf8vctrsviridisviridisLitevpcvroomwithrxfunxgxrxml2yaml