NEWS

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nlmixr2 7.0.1 (2026-08-04)

• The mixture-models article documents reading the fitted component off the fit table (a mixest/mixnum output variable), which needs an rxode2 carrying nlmixr2/rxode2#1358; it also now appears in the Articles menu, which it was missing from.

• nlmixr2CheckInstall() no longer fails when the repositories cannot be queried for package updates. Both an unreachable repository and an error from utils::old.packages() itself (seen on Windows, where pkgType is "both" and R's internal .available.both() can fail with "subscript out of bounds" when the source and binary indexes disagree) are now reported as "updates could not be checked" instead of stopping the check.

• nlmixr2CheckInstall() messages are escaped before they are handed to cli, so paths or command output containing { or } are shown literally rather than being interpreted as glue expressions.

nlmixr2 7.0.0

• Optionally import more packages to support nlmixr2 ecosystem

• Match nlmixr2est

• Do not show the packages that were optionally included in the secondary list of packages, instead show them being imported with an open circle. Required packages are shown with a star.

• Removed duplicated entries from the optional package list so that nlmixr2CheckInstall() and the startup banner no longer report pmxNODE, nlmixr2auto and nlmixr2autoinit twice.

• nlmixr2 now requires R 4.1.0 or later (the native |> pipe is used internally); magrittr is no longer imported. The %>% pipe was never exported by nlmixr2 itself, so this does not change the package's user-visible API.

nlmixr2 5.0.0 (2025-11-30)

• Import everything with the nlmixr2 5.0 file format

nlmixr2 4.0.1 (2025-08-29)

• Added posologyr to the optional packages

nlmixr2 4.0

• Change to a verse style package.

nlmixr2 3.0.2 (2025-02-20)

• Change saemControl() and other options to reflect the nlmixr2est default options

• Update authors to reflect current team.

• Export rxSetSeed()

nlmixr2 3.0.1 (2024-10-28)

• Remove backwardSearch, covarSearchAuto and forwardSearch re-exports since they no longer exist in nlmixr2extra

• Remove rxode2parse suggested dependency

nlmixr2 3.0.0 (2024-09-18)

• Re-export the new profiling from nlmixr2extra

nlmixr2 2.1.2 (2024-05-30)

• Re-export the population only estimation control methods.

nlmixr2 2.1.1 (2024-02-01)

• Work with systems (like intel c++) where linCmt() linear compartmental models do not have gradients.

nlmixr2 2.1.0 (2024-01-09)

• Reexports etExpand(), model()<- and ini()<-

nlmixr2 2.0.9 (2023-02-21)

• The new function nlmixr2CheckInstall() helps to check if your installation is setup correctly with the required compilers and packages.

• This version adds crayon as an imported dependency

nlmixr2 2.0.8 (2022-10-23)

• This release has a bug fix that captures the model name correctly when called directly from nlmixr::nlmixr2 instead nlmixr2est::nlmixr2

• This also exports the new vpc functions, ie vpcTad() etc

nlmixr2 2.0.7 (2022-06-27)

• nlmixr2 now re-exports logit so that certain models will work with a simple library(nlmixr2) instead of library(rxode2);library(nlmixr2)

• vpcSim() now exports the new nretry option for more robust control of vpcSim()

• Update documentation to mention the package names that work with nlmixr2, like xpose.nlmixr2 instead of xpose.nlmixr

• Manual hard re-export of nlmixr2est::nlmixr2 to allow pkgdown to document this function.

nlmixr2 2.0.6 (2022-05-24)

• nlmixr2 is an umbrella package to include the lower level packages rxode2, nlmixr2est, nlmixr2extra, and nlmixr2plot

• Added a NEWS.md file to track changes to the package.