Package: nlmixr2lib 0.2.0.9000

Bill Denney

nlmixr2lib: A Model Library for 'nlmixr2'

A model library for 'nlmixr2'. The models include (and plan to include) pharmacokinetic, pharmacodynamic, and disease models used in pharmacometrics. Where applicable, references for each model are included in the meta-data for each individual model. The package also includes model composition and modification functions to make model updates easier.

Authors:Richard Hooijmaijers [aut], Matthew Fidler [aut], Bill Denney [aut, cre]

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nlmixr2lib.pdf |nlmixr2lib.html✨
nlmixr2lib/json (API)
NEWS

# Install 'nlmixr2lib' in R:

install.packages('nlmixr2lib', repos = c('https://nlmixr2.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/nlmixr2/nlmixr2lib/issues

Datasets:

modeldb - Model library for nlmixr2

On CRAN:

30 exports 5 stars 1.71 score 67 dependencies 230 downloads

Last updated 8 days agofrom:cd58212f1a

Exports:addComp addDepot addDirToModelDb addEta addFileToModelDb addResErr addTransit assertCompartmentExists assertCompartmentName assertParameterValue assertRxUi assertRxUiEstimatedResiduals assertRxUiMixedOnly assertRxUiMuRefOnly assertRxUiNormal assertRxUiPopulationOnly assertRxUiPrediction assertRxUiRandomOnIdOnly assertRxUiSingleEndpoint assertRxUiTransformNormal assertVariableName convertMM modellib readModelDb removeComp removeDepot removeTransit searchReplace searchReplaceHelper updateOncologyXenograftSimeoni2004

Dependencies:backports BH cachem checkmate cli colorspace crayon data.table digest dparser evaluate fansi farver fastmap ggplot2 glue gtable highr inline isoband knitr labeling lattice lazyeval lbfgsb3c lifecycle lotri magrittr MASS Matrix memoise mgcv minqa munsell n1qn1 nlme nlmixr2data nlmixr2est numDeriv pillar pkgconfig PreciseSums qs R6 RApiSerialize RColorBrewer Rcpp RcppArmadillo RcppEigen RcppParallel rex rlang rxode2 rxode2ll scales sitmo StanHeaders stringfish symengine sys tibble utf8 vctrs viridisLite withr xfun yaml

Creating a model library

Rendered fromcreate-model-library.Rmdusingknitr::rmarkdownon Jul 18 2024.

Last update: 2024-06-29
Started: 2022-09-16

List of models

Rendered fromlist-of-models.Rmdusingknitr::rmarkdownon Jul 18 2024.

Last update: 2023-04-22
Started: 2023-04-22

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
To add additional compartments to the model	addComp
To convert from infusion/intravenous administration to first-order oral absorption	addDepot
Add a directory to the modeldb	addDirToModelDb addFileToModelDb
Add random effects to a model	addEta
Add residual error to a model	addResErr
To add transit compartments to the model	addTransit
Convert models from linear elimination to MM elimination	convertMM
Model library for nlmixr2	modeldb
Get the model from the model library	modellib
Read a model from the nlmixr2 model database	readModelDb
To remove peripheral compartments from the model	removeComp
To convert from first order oral absorption to IV/Intravenous	removeDepot
To remove transit compartments from the model	removeTransit
Search within a model to replace part of the model	searchReplace searchReplaceHelper
Update an oncology xenograft model based on Simeoni 2004	updateOncologyXenograftSimeoni2004