Package: nonmem2rx 0.1.4.9000

Matthew Fidler

nonmem2rx: 'nonmem2rx' Converts 'NONMEM' Models to 'rxode2'

'NONMEM' has been a tool for running nonlinear mixed effects models since the 80s and is still used today (Bauer 2019 <doi:10.1002/psp4.12404>). This tool allows you to convert 'NONMEM' models to 'rxode2' (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) and with simple models 'nlmixr2' syntax (Fidler et al (2019) <doi:10.1002/psp4.12445>). The 'nlmixr2' syntax requires the residual specification to be included and it is not always translated. If available, the 'rxode2' model will read in the 'NONMEM' data and compare the simulation for the population model ('PRED') individual model ('IPRED') and residual model ('IWRES') to immediately show how well the translation is performing. This saves the model development time for people who are creating an 'rxode2' model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a 'rxode2' model. This is complementary to the 'babelmixr2' package that translates 'nlmixr2' models to 'NONMEM' and can convert the objects converted from 'nonmem2rx' to a full 'nlmixr2' fit.

Authors:Matthew Fidler [aut, cre], Philip Delff [ctb], Gabriel Staples [ctb]

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Bug tracker:https://github.com/nlmixr2/nonmem2rx/issues

On CRAN:

nlmixr2nonmempharmacometricsrxode2

27 exports 9 stars 2.17 score 71 dependencies 1 dependents 833 downloads

Last updated 2 months agofrom:3721d2228b

Exports:%>%as.nonmem2rxautoplotexpitinilogitlotrimodelmodel<-nmcovnmextnminfonmlstnmtabnmxmlnmxmlCovnmxmlOmeganmxmlSigmanmxmlThetanonmem2rxnonmem2rxRecrxodeRxODErxode2rxRenamerxSolverxUiGet

Dependencies:backportsBHcachemcheckmateclicolorspacecpp11crayondata.tabledigestdparserevaluatefansifarverfastmapggforceggplot2gluegtablehighrinlineisobandknitrlabelinglatticelazyevallifecyclelotrimagrittrMASSMatrixmemoisemgcvmunsellnlmepillarpkgconfigpolyclipPreciseSumsqsR6RApiSerializeRColorBrewerRcppRcppArmadilloRcppEigenRcppParallelrexrlangrxode2rxode2etrxode2llrxode2parserxode2randomscalessitmoStanHeadersstringfishsymenginesyssystemfontstibbletidyselecttweenrutf8vctrsviridisLitewithrxfunxml2yaml