Package: nlmixr2data 2.0.9

Matthew Fidler

nlmixr2data: Nonlinear Mixed Effects Models in Population PK/PD, Data

Datasets for 'nlmixr2' and 'rxode2'. 'nlmixr2' is used for fitting and comparing nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).

Authors:Matthew Fidler [aut, cre], Rik Schoemaker [ctb], Kyle Baron [ctb], Thierry Wendling [ctb], Ted Grasella [ctb], C Weil [ctb], Yaning Wang [ctb], R O'Reilly [ctb], David D'Argenio [ctb], Rodriguez-Vera [ctb], D Gaver [ctb], Yuan Xiong [ctb], Wenping Wang [aut]

nlmixr2data_2.0.9.tar.gz
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nlmixr2data_2.0.9.tgz(r-4.4-any)nlmixr2data_2.0.9.tgz(r-4.3-any)
nlmixr2data_2.0.9.tar.gz(r-4.5-noble)nlmixr2data_2.0.9.tar.gz(r-4.4-noble)
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nlmixr2data.pdf |nlmixr2data.html
nlmixr2data/json (API)
NEWS

# Install nlmixr2data in R:
install.packages('nlmixr2data', repos = c('https://nlmixr2.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/nlmixr2/nlmixr2data/issues

Datasets:
  • Bolus_1CPT - 1 Compartment Model Simulated Data from ACOP 2016
  • Bolus_1CPTMM - 1 Compartment Model w/ Michaelis-Menten Elimination
  • Bolus_2CPT - 2 Compartment Model
  • Bolus_2CPTMM - 2 Compartment Model with Michaelis-Menten Clearance
  • Infusion_1CPT - 1 Compartment Model Simulated Data from ACOP 2016
  • Infusion_1CPTMM - 1 Compartment Model w/MM elimination Simulated Data from ACOP 2016
  • Infusion_2CPT - 2 Compartment Model with Infusion Simulated Data from ACOP 2016
  • Infusion_2CPTMM - 2 Compartment Model w/MM elimination Simulated Data from ACOP 2016
  • Oral_1CPT - 1 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
  • Oral_1CPTMM - 1 Compartment Model w/ Oral Absorption & Michaelis-Menten Elimination
  • Oral_2CPT - 2 Compartment Model with Oral Absorption Simulated Data from ACOP 2016
  • Oral_2CPTMM - 1 Compartment Model w/ Oral Absorption & Michaelis-Menten Elimination
  • Wang2007 - Simulated Data Set for comparing objective functions
  • invgaussian - Inverse Guassian absorption model
  • mavoglurant - Mavoglurant PK data
  • metabolite - Parent/Metabolite dataset
  • nimoData - Nimotuzumab PK data
  • nmtest - One compartment test dataset showing NONMEM 7.4.3 output
  • pheno_sd - Single Dose Phenobarbitol PK/PD
  • pump - Pump failure example dataset
  • rats - Pregnant Rat Diet Experiment
  • theo_md - Multiple dose theophylline PK data
  • theo_sd - Multiple dose theophylline PK data
  • warfarin - Warfarin PK/PD data
  • wbcSim - Simulated Friberg Myelosuppression model

On CRAN:

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Last updated 5 months agofrom:f7bd1f7b1b893f30b8239420af277f3275139611

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