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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "rxode2ll" in publications use:'
type: software
license: GPL-3.0-or-later
title: 'rxode2ll: Log-Likelihood Functions for ''rxode2'''
version: 2.0.11.9000
identifiers:
- type: doi
  value: 10.32614/CRAN.package.rxode2ll
- type: url
  value: https://github.com/nlmixr2/rxode2ll/
abstract: Provides the log-likelihoods with gradients from 'stan' (Carpenter et al
  (2015), <arXiv:1509.07164>) needed for generalized log-likelihood estimation in
  'nlmixr2' (Fidler et al (2019) <https://doi.org/10.1002/psp4.12445>). This is split
  of to reduce computational burden of recompiling 'rxode2' (Wang, Hallow and James
  (2016) <https://doi.org/10.1002/psp4.12052>) which runs the 'nlmixr2' models during
  estimation.
authors:
- family-names: Fidler
  given-names: Matthew L.
  email: matthew.fidler@gmail.com
  orcid: https://orcid.org/0000-0001-8538-6691
preferred-citation:
  type: article
  title: 'A Tutorial on RxODE: Simulating Differential Equation Pharmacometric Models
    in R'
  authors:
  - family-names: Wang
    given-names: Wenping
  - family-names: Hallow
    given-names: K Melissa
  - family-names: James
    given-names: David A
  journal: 'CPT: Pharmacometrics \& Systems Pharmacology'
  year: '2015'
  volume: '5'
  issue: '1'
  month: '11'
  abstract: This tutorial presents the application of an R package, RxODE, that facilitates
    quick, efficient simulations of ordinary differential equation models completely
    within R. Its application is illustrated through simulation of design decision
    effects on an adaptive dosing regimen. The package provides an efficient, versatile
    way to specify dosing scenarios and to perform simulation with variability with
    minimal custom coding. Models can be directly translated to Rshiny applications
    to facilitate interactive, real-time evaluation/iteration on simulation scenarios.
  issn: 2163-8306
  publisher:
    name: John Wiley and Sons Inc.
    address: Hoboken
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728294/
  start: '3'
  end: '10'
repository: https://nlmixr2.r-universe.dev
repository-code: https://github.com/nlmixr2/rxode2ll/issues/
commit: 6e6c55d0874eda811fa78260e36d262c2533a43a
url: https://nlmixr2.github.io/rxode2ll/
contact:
- family-names: Fidler
  given-names: Matthew L.
  email: matthew.fidler@gmail.com
  orcid: https://orcid.org/0000-0001-8538-6691