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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "rxode2" in publications use:'
type: software
license: GPL-3.0-or-later
title: 'rxode2: Facilities for Simulating from ODE-Based Models'
version: 3.0.0
identifiers:
- type: doi
  value: 10.32614/CRAN.package.rxode2
- type: url
  value: https://github.com/nlmixr2/rxode2/
abstract: 'Facilities for running simulations from ordinary differential equation
  (''ODE'') models, such as pharmacometrics and other compartmental models. A compilation
  manager translates the ODE model into C, compiles it, and dynamically loads the
  object code into R for improved computational efficiency. An event table object
  facilitates the specification of complex dosing regimens (optional) and sampling
  schedules. NB: The use of this package requires both C and Fortran compilers, for
  details on their use with R please see Section 6.3, Appendix A, and Appendix D in
  the "R Administration and Installation" manual. Also the code is mostly released
  under GPL. The ''VODE'' and ''LSODA'' are in the public domain. The information
  is available in the inst/COPYRIGHTS.'
authors:
- family-names: Fidler
  given-names: Matthew L.
  email: matthew.fidler@gmail.com
  orcid: https://orcid.org/0000-0001-8538-6691
- family-names: Wang
  given-names: Wenping
  email: wwang8198@gmail.com
- family-names: Hallow
  given-names: Melissa
  email: hallowkm@uga.edu
preferred-citation:
  type: manual
  title: 'RxODE: Facilities for Simulating from ODE-Based Models'
  authors:
  - family-names: Fidler
    given-names: Matthew L.
    email: matthew.fidler@gmail.com
    orcid: https://orcid.org/0000-0001-8538-6691
  - family-names: Hallow
    given-names: Melissa
    email: hallowkm@uga.edu
  - family-names: Wilkins
    given-names: Justin
  - family-names: Wang
    given-names: Wenping
    email: wwang8198@gmail.com
  year: '2024'
  notes: R package version 3.0.0
  url: https://CRAN.R-project.org/package=rxode2
repository: https://nlmixr2.r-universe.dev
repository-code: https://github.com/nlmixr2/rxode2/issues/
commit: f8a519eb013ac1d338cfd1f8e8a3bcc655a588b6
url: https://nlmixr2.github.io/rxode2/
contact:
- family-names: Fidler
  given-names: Matthew L.
  email: matthew.fidler@gmail.com
  orcid: https://orcid.org/0000-0001-8538-6691
references:
- type: article
  title: 'A Tutorial on RxODE: Simulating Differential Equation Pharmacometric Models
    in R'
  authors:
  - family-names: Wang
    given-names: Wenping
  - family-names: Hallow
    given-names: K Melissa
  - family-names: James
    given-names: David A
  journal: 'CPT: Pharmacometrics \& Systems Pharmacology'
  year: '2015'
  volume: '5'
  issue: '1'
  month: '11'
  abstract: This tutorial presents the application of an R package, RxODE, that facilitates
    quick, efficient simulations of ordinary differential equation models completely
    within R. Its application is illustrated through simulation of design decision
    effects on an adaptive dosing regimen. The package provides an efficient, versatile
    way to specify dosing scenarios and to perform simulation with variability with
    minimal custom coding. Models can be directly translated to Rshiny applications
    to facilitate interactive, real-time evaluation/iteration on simulation scenarios.
  issn: 2163-8306
  publisher:
    name: John Wiley and Sons Inc.
    address: Hoboken
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728294/
  start: '3'
  end: '10'