Package: nonmem2rx
Type: Package
Title: Converts 'NONMEM' Models to 'rxode2'
Version: 0.1.12
Maintainer: Matthew Fidler <matthew.fidler@gmail.com>
Authors@R: c(person("Matthew","Fidler", role = c("aut", "cre"), email = "matthew.fidler@gmail.com", comment=c(ORCID="0000-0001-8538-6691")),
    person("Philip", "Delff", email = "philip@delff.dk",role = c("ctb")),
    person("Gabriel", "Staples", role="ctb", comment="string insensitive compare"))
Description: 'NONMEM' has been a tool for running nonlinear mixed
        effects models since the 80s and is still used today (Bauer
        2019 <doi:10.1002/psp4.12404>). This tool allows you to convert
        'NONMEM' models to 'rxode2' (Wang, Hallow and James (2016)
        <doi:10.1002/psp4.12052>) and with simple models 'nlmixr2'
        syntax (Fidler et al (2019) <doi:10.1002/psp4.12445>). The
        'nlmixr2' syntax requires the residual specification to be
        included and it is not always translated. If available, the
        'rxode2' model will read in the 'NONMEM' data and compare the
        simulation for the population model ('PRED') individual model
        ('IPRED') and residual model ('IWRES') to immediately show how
        well the translation is performing. This saves the model
        development time for people who are creating an 'rxode2' model
        manually.  Additionally, this package reads in all the
        information to allow simulation with uncertainty (that is the
        number of observations, the number of subjects, and the
        covariance matrix) with a 'rxode2' model.  This is
        complementary to the 'babelmixr2' package that translates
        'nlmixr2' models to 'NONMEM' and can convert the objects
        converted from 'nonmem2rx' to a full 'nlmixr2' fit.
License: GPL (>= 3)
URL: https://nlmixr2.github.io/nonmem2rx/,
        https://github.com/nlmixr2/nonmem2rx/
Encoding: UTF-8
Depends: R (>= 4.1.0)
LinkingTo: dparser, Rcpp, rxode2
Imports: checkmate, digest, dparser, lotri, Rcpp, rxode2 (>= 5.1.8),
        magrittr, cli, tools, utils, data.table, xml2, ggplot2,
        ggforce, crayon
Suggests: ellmer, devtools, testthat (>= 3.0.0), nonmemica, NMdata,
        nonmem2R, withr, nlme, dplyr, xgxr, vdiffr, knitr, rmarkdown,
        spelling, nlmixr2est
Config/testthat/edition: 3
Roxygen: list(markdown = TRUE)
VignetteBuilder: knitr, rmarkdown
Language: en-US
Config/roxygen2/version: 8.1.0
Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev make
        libxml2-dev
Repository: https://nlmixr2.r-universe.dev
Date/Publication: 2026-10-13 11:44:02 UTC
RemoteUrl: https://github.com/nlmixr2/nonmem2rx
RemoteRef: HEAD
RemoteSha: ef533078856dbdf2f9accfbe131f46bfaee87c28
NeedsCompilation: yes
Packaged: 2026-10-13 12:05:16 UTC; root
Author: Matthew Fidler [aut, cre] (ORCID:
    <https://orcid.org/0000-0001-8538-6691>),
  Philip Delff [ctb],
  Gabriel Staples [ctb] (string insensitive compare)