{ "_id": "6a635852aecbde9870bb26d2", "Package": "rxode2", "Version": "5.1.5", "Title": "Facilities for Simulating from ODE-Based Models", "Authors@R": "c(\nperson(\"Matthew L.\",\"Fidler\", role = c(\"aut\", \"cre\"), email = \"matthew.fidler@gmail.com\", comment=c(ORCID=\"0000-0001-8538-6691\")),\nperson(\"Wenping\", \"Wang\", role = c(\"aut\"), email = \"wwang8198@gmail.com\"),\nperson(\"Aaron\", \"Collier\", role=\"ctb\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Alan\", \"Hindmarsh\",role=\"ctb\"),\nperson(\"Arun\", \"Srinivasan\", role=\"ctb\", email=\"arunkumar.sriniv@gmail.com\"),\nperson(\"Ashley\", \"Crawford\", role=\"ctb\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Awad H.\", \"Al-Mohy\",role=\"ctb\"),\nperson(\"Bill\", \"Denney\", email=\"wdenney@humanpredictions.com\", role=\"ctb\", comment=c(ORCID=\"0000-0002-5759-428X\")),\nperson(\"Cleve\", \"Moler\", role=\"ctb\"),\nperson(\"Cody J.\", \"Balos\", role=\"ctb\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Dan\", \"Shumaker\", role=\"ctb\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Daniel\", \"Kaschek\", email=\"daniel.kaschek@gmail.com\", role=\"ctb\"),\nperson(\"Daniel R.\", \"Reynolds\", role=\"ctb\", comment=\"SUNDIALS/CVODE\"),\nperson(\"David\", \"Cooley\", role=\"ctb\"),\nperson(\"David J.\", \"Gardner\", role=\"ctb\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Drew\", \"Schmidt\", role=\"ctb\"),\nperson(\"Ernst\", \"Hairer\", role=\"ctb\"),\nperson(\"Gabriel\", \"Staples\", role=\"ctb\"),\nperson(\"Gerhard\", \"Wanner\", role=\"ctb\"),\nperson(\"Gilbert\", \"Stewart\", role=\"ctb\"),\nperson(\"Goro\", \"Fuji\", role=\"ctb\", email=\"gfuji@cpan.org\"),\nperson(\"Hadley\", \"Wickham\", role=\"ctb\"),\nperson(\"Hidde\", \"van de Beek\", role=\"ctb\", email=\"hiddevdbeek@icloud.com\"),\nperson(\"Igor\", \"Kushnir\", email=\"igorkuo@gmail.com\", role=\"ctb\"),\nperson(\"Imperial College of Science, Technology and Medicine\", role=\"cph\"),\nperson(\"Jack\", \"Dongarra\", role=\"ctb\"),\nperson(\"Jacob\", \"Williams\", role=\"ctb\"),\nperson(\"Jim\", \"Bunch\", role=\"ctb\"),\nperson(\"Karline\", \"Soetaert\", role=\"ctb\"),\nperson(\"Kevin\", \"Ushey\", role=\"ctb\"),\nperson(\"Lawrence Livermore National Security\", role=\"cph\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Linda\", \"Petzold\", role=\"ctb\"),\nperson(\"Mark M.\", \"Baum\", role=\"ctb\"),\nperson(\"Martin\", \"Maechler\", role=\"ctb\"),\nperson(\"Matt\", \"Dowle\", role=\"ctb\", email=\"mattjdowle@gmail.com\"),\nperson(\"Matteo\", \"Fasiolo\", email = \"matteo.fasiolo@gmail.com\", role = \"ctb\"),\nperson(\"Melissa\", \"Hallow\", role = \"aut\", email = \"hallowkm@uga.edu\"),\nperson(\"Michel\", \"Lang\", , \"michellang@gmail.com\", role = \"ctb\"),\nperson(\"Morwenn\",\"\", role=\"ctb\"),\nperson(\"Nicholas J.\", \"Higham\",role=\"ctb\"),\nperson(\"Omar\", \"Elashkar\", email=\"omar.i.elashkar@gmail.com\", role=\"ctb\"),\nperson(\"Peter N.\", \"Brown\", role=\"ctb\"),\nperson(\"Radu\", \"Serban\", role=\"ctb\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Rich\", \"FitzJohn\", role=\"ctb\", email=\"rich.fitzjohn@gmail.com\"),\nperson(\"Richard\", \"Upton\", role = \"ctb\"),\nperson(\"Roger B.\", \"Sidje\", role=\"ctb\"),\nperson(\"Scott D.\", \"Cohen\", role=\"ctb\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Simon\", \"Frost\", role=\"ctb\"),\nperson(\"Slaven\", \"Peles\", role=\"ctb\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Southern Methodist University\", role=\"cph\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Thomas\", \"Petzoldt\", role=\"ctb\"),\nperson(\"University of Maryland Baltimore County\", role=\"cph\", comment=\"SUNDIALS/CVODE\"),\nperson(\"Wes\", \"Hinsley\", role=\"ctb\"),\nperson(\"Woodrow\", \"Setzer\", role=\"ctb\"),\nperson(\"Yu\", \"Feng\", role=\"ctb\"),\nperson(\"Zufar\", \"Mulyukov\", role=\"ctb\", email=\"zufar.mulyukov@novartis.com\"))", "Maintainer": "Matthew L. Fidler ", "Description": "Facilities for running simulations from ordinary\ndifferential equation ('ODE') models, such as pharmacometrics\nand other compartmental models. A compilation manager\ntranslates the ODE model into C, compiles it, and dynamically\nloads the object code into R for improved computational\nefficiency. An event table object facilitates the\nspecification of complex dosing regimens (optional) and\nsampling schedules. NB: The use of this package requires both\nC and Fortran compilers, for details on their use with R please\nsee Section 6.3, Appendix A, and Appendix D in the \"R\nAdministration and Installation\" manual. Also the code is\nmostly released under GPL. The 'VODE' and 'LSODA' are in the\npublic domain. The vendored 'SUNDIALS' 'CVODE' sources and\nheaders are released under the BSD-3-Clause license. The\ninformation is available in the inst/COPYRIGHTS.", "BugReports": "https://github.com/nlmixr2/rxode2/issues/", "NeedsCompilation": "yes", "VignetteBuilder": "knitr", "License": "GPL (>= 3)", "URL": "https://nlmixr2.github.io/rxode2/,\nhttps://github.com/nlmixr2/rxode2/", "Biarch": "true", "Encoding": "UTF-8", "LazyData": "true", "Language": "en-US", "Roxygen": "list(markdown = TRUE)", "Config/testthat/edition": "3", "Config/roxygen2/version": "8.0.0", "Config/pak/sysreqs": "cmake make", "Repository": "https://nlmixr2.r-universe.dev", "Date/Publication": "2026-07-24 09:18:49 UTC", "RemoteUrl": "https://github.com/nlmixr2/rxode2", "RemoteRef": "HEAD", "RemoteSha": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "Packaged": { "Date": "2026-07-24 11:58:04 UTC", "User": "root" }, "Author": "Matthew L. Fidler [aut, cre] (ORCID:\n),\nWenping Wang [aut],\nAaron Collier [ctb] (SUNDIALS/CVODE),\nAlan Hindmarsh [ctb],\nArun Srinivasan [ctb],\nAshley Crawford [ctb] (SUNDIALS/CVODE),\nAwad H. Al-Mohy [ctb],\nBill Denney [ctb] (ORCID: ),\nCleve Moler [ctb],\nCody J. Balos [ctb] (SUNDIALS/CVODE),\nDan Shumaker [ctb] (SUNDIALS/CVODE),\nDaniel Kaschek [ctb],\nDaniel R. Reynolds [ctb] (SUNDIALS/CVODE),\nDavid Cooley [ctb],\nDavid J. Gardner [ctb] (SUNDIALS/CVODE),\nDrew Schmidt [ctb],\nErnst Hairer [ctb],\nGabriel Staples [ctb],\nGerhard Wanner [ctb],\nGilbert Stewart [ctb],\nGoro Fuji [ctb],\nHadley Wickham [ctb],\nHidde van de Beek [ctb],\nIgor Kushnir [ctb],\nImperial College of Science, Technology and Medicine [cph],\nJack Dongarra [ctb],\nJacob Williams [ctb],\nJim Bunch [ctb],\nKarline Soetaert [ctb],\nKevin Ushey [ctb],\nLawrence Livermore National Security [cph] (SUNDIALS/CVODE),\nLinda Petzold [ctb],\nMark M. Baum [ctb],\nMartin Maechler [ctb],\nMatt Dowle [ctb],\nMatteo Fasiolo [ctb],\nMelissa Hallow [aut],\nMichel Lang [ctb],\nMorwenn [ctb],\nNicholas J. Higham [ctb],\nOmar Elashkar [ctb],\nPeter N. Brown [ctb],\nRadu Serban [ctb] (SUNDIALS/CVODE),\nRich FitzJohn [ctb],\nRichard Upton [ctb],\nRoger B. Sidje [ctb],\nScott D. Cohen [ctb] (SUNDIALS/CVODE),\nSimon Frost [ctb],\nSlaven Peles [ctb] (SUNDIALS/CVODE),\nSouthern Methodist University [cph] (SUNDIALS/CVODE),\nThomas Petzoldt [ctb],\nUniversity of Maryland Baltimore County [cph] (SUNDIALS/CVODE),\nWes Hinsley [ctb],\nWoodrow Setzer [ctb],\nYu Feng [ctb],\nZufar Mulyukov [ctb]", "_user": "nlmixr2", "_type": "src", "_file": "rxode2_5.1.5.tar.gz", "_fileid": "https://r2.ropensci.org/b00d6301a2b6b5d2aadbf46a2c98baf1ad195daaa7abe03d42b085b57b31a5f9", "_filesize": 5244466, "_sha256": "b00d6301a2b6b5d2aadbf46a2c98baf1ad195daaa7abe03d42b085b57b31a5f9", "_expires": "2026-11-01T12:19:28.000Z", "_created": "2026-07-24T11:58:04.000Z", "_published": "2026-07-24T20:06:55.308Z", "_jobs": [ { "job": 89476252786, "time": 546, "config": "linux-devel-arm64", "r": "4.7.0", "check": "OK", "artifact": "8596128296" }, { "job": 89476251575, "time": 499, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "8596110168" }, { "job": 89476251504, "time": 538, "config": "linux-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "8596125126" }, { "job": 89476251527, "time": 574, "config": "linux-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "8596139694" }, { "job": 89476251536, "time": 418, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "ERROR", "artifact": "8596077809" }, { "job": 89476251480, "time": 939, "config": "macos-oldrel-x86_64", "r": "4.5.3", "check": "ERROR", "artifact": "8596275151" }, { "job": 89476251494, "time": 575, "config": "macos-release-arm64", "r": "4.6.1", "check": "ERROR", "artifact": "8596139811" }, { "job": 89476251523, "time": 826, "config": "macos-release-x86_64", "r": "4.6.1", "check": "ERROR", "artifact": "8596232902" }, { "job": 89473571260, "time": 881, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "8595923447" }, { "job": 89476251406, "time": 464, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "8596096358" }, { "job": 89476251460, "time": 568, "config": "windows-devel-x86_64", "r": "4.7.0", "check": "FAIL", "artifact": "" }, { "job": 89476251434, "time": 596, "config": "windows-oldrel-x86_64", "r": "4.5.3", "check": "FAIL", "artifact": "" }, { "job": 89476251426, "time": 600, "config": "windows-release-x86_64", "r": "4.6.1", "check": "FAIL", "artifact": "" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288", "_status": "success", "_upstream": "https://github.com/nlmixr2/rxode2", "_commit": { "id": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "author": "mattfidler ", "committer": "mattfidler ", "message": "Update cran comments\n", "time": 1784884729 }, "_maintainer": { "name": "Matthew L. Fidler", "email": "matthew.fidler@gmail.com", "login": "mattfidler", "description": "Also a Novartis employee; Can reach me at my Novartis email: matt.fidler@novartis.com", "uuid": 514778, "orcid": "0000-0001-8538-6691" }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 4.1.0", "role": "Depends" }, { "package": "sitmo", "role": "LinkingTo" }, { "package": "lotri", "version": ">= 1.0.0", "role": "LinkingTo" }, { "package": "PreciseSums", "version": ">= 0.7", "role": "LinkingTo" }, { "package": "Rcpp", "role": "LinkingTo" }, { "package": "RcppArmadillo", "version": ">= 0.9.300.2.0", "role": "LinkingTo" }, { "package": "BH", "role": "LinkingTo" }, { "package": "RcppParallel", "role": "LinkingTo" }, { "package": "RcppEigen", "version": ">= 0.3.3.9.2", "role": "LinkingTo" }, { "package": "dparser", "version": ">= 1.3.1-12", "role": "LinkingTo" }, { "package": "StanHeaders", "version": ">= 2.21.0.7", "role": "LinkingTo" }, { "package": "PreciseSums", "version": ">= 0.7", "role": "Imports" }, { "package": "Rcpp", "version": ">= 0.12.3", "role": "Imports" }, { "package": "backports", "role": "Imports" }, { "package": "cli", "version": ">= 2.0.0", "role": "Imports" }, { "package": "checkmate", "role": "Imports" }, { "package": "ggplot2", "version": ">= 3.4.0", "role": "Imports" }, { "package": "inline", "role": "Imports" }, { "package": "lotri", "version": ">= 1.0.4", "role": "Imports" }, { "package": "memoise", "role": "Imports" }, { "package": "methods", "role": "Imports" }, { "package": "mirai", "role": "Imports" }, { "package": "rex", "role": "Imports" }, { "package": "sys", "role": "Imports" }, { "package": "tools", "role": "Imports" }, { "package": "utils", "role": "Imports" }, { "package": "dparser", "version": ">= 1.3.1-12", "role": "Imports" }, { "package": "rxode2ll", "version": ">= 2.0.16", "role": "Imports" }, { "package": "data.table", "version": ">= 1.12.4", "role": "Imports" }, { "package": "vctrs", "role": "Imports" }, { "package": "stats", "role": "Imports" }, { "package": "Matrix", "role": "Suggests" }, { "package": "DT", "role": "Suggests" }, { "package": "covr", "role": "Suggests" }, { "package": "crayon", "role": "Suggests" }, { "package": "curl", "role": "Suggests" }, { "package": "digest", "role": "Suggests" }, { "package": "dplyr", "version": ">= 0.8.0", "role": "Suggests" }, { "package": "ggrepel", "role": "Suggests" }, { "package": "gridExtra", "role": "Suggests" }, { "package": "htmltools", "role": "Suggests" }, { "package": "knitr", "role": "Suggests" }, { "package": "learnr", "role": "Suggests" }, { "package": "microbenchmark", "role": "Suggests" }, { "package": "nlme", "role": "Suggests" }, { "package": "remotes", "role": "Suggests" }, { "package": "rlang", "role": "Suggests" }, { "package": "rmarkdown", "role": "Suggests" }, { "package": "scales", "role": "Suggests" }, { "package": "shiny", "role": "Suggests" }, { "package": "stringi", "role": "Suggests" }, { "package": "symengine", "role": "Suggests" }, { "package": "testthat", "role": "Suggests" }, { "package": "tidyr", "role": "Suggests" }, { "package": "usethis", "role": "Suggests" }, { "package": "withr", "role": "Suggests" }, { "package": "xgxr", "role": "Suggests" }, { "package": "pillar", "role": "Suggests" }, { "package": "tibble", "role": "Suggests" }, { "package": "units", "version": ">= 0.6-0", "role": "Suggests" }, { "package": "rsconnect", "role": "Suggests" }, { "package": "devtools", "role": "Suggests" }, { "package": "patchwork", "role": "Suggests" }, { "package": "nlmixr2data", "role": "Suggests" }, { "package": "lifecycle", "role": "Suggests" }, { "package": "kableExtra", "role": "Suggests" }, { "package": "pmxTools", "role": "Suggests" }, { "package": "rootSolve", "role": "Suggests" }, { "package": "arrow", "role": "Suggests" }, { "package": "fst", "role": "Suggests" }, { "package": "duckdb", "role": "Suggests" }, { "package": "DBI", "role": "Suggests" } ], "_owner": "nlmixr2", "_selfowned": true, "_usedby": 19, "_updates": [ { "week": "2025-30", "n": 15 }, { "week": "2025-31", "n": 3 }, { "week": "2025-32", "n": 1 }, { "week": "2025-33", "n": 5 }, { "week": "2025-34", "n": 1 }, { "week": "2025-35", "n": 4 }, { "week": "2025-36", "n": 3 }, { "week": "2025-37", "n": 1 }, { "week": "2025-39", "n": 1 }, { "week": "2025-40", "n": 1 }, { "week": "2025-41", "n": 2 }, { "week": "2025-42", "n": 4 }, { "week": "2025-47", "n": 1 }, { "week": "2025-48", "n": 14 }, { "week": "2025-49", "n": 30 }, { "week": "2025-50", "n": 1 }, { "week": "2026-01", "n": 3 }, { "week": "2026-04", "n": 11 }, { "week": "2026-07", "n": 1 }, { "week": "2026-08", "n": 2 }, { "week": "2026-09", "n": 2 }, { "week": "2026-11", "n": 1 }, { "week": "2026-12", "n": 14 }, { "week": "2026-13", "n": 3 }, { "week": "2026-14", "n": 12 }, { "week": "2026-15", "n": 1 }, { "week": "2026-16", "n": 1 }, { "week": "2026-17", "n": 1 }, { "week": "2026-18", "n": 10 }, { "week": "2026-19", "n": 17 }, { "week": "2026-20", "n": 18 }, { "week": "2026-21", "n": 28 }, { "week": "2026-22", "n": 22 }, { "week": "2026-23", "n": 9 }, { "week": "2026-24", "n": 9 }, { "week": "2026-25", "n": 8 }, { "week": "2026-26", "n": 4 }, { "week": "2026-27", "n": 8 }, { "week": "2026-28", "n": 27 }, { "week": "2026-29", "n": 28 }, { "week": "2026-30", "n": 16 } ], "_tags": [ { "name": "v4.1.0", "date": "2025-08-29" }, { "name": "v4.1.1", "date": "2025-10-08" }, { "name": "v5.0.0", "date": "2025-11-27" }, { "name": "v5.0.1", "date": "2025-12-06" }, { "name": "v5.0.2", "date": "2026-03-19" }, { "name": "v5.1.1", "date": "2026-05-27" }, { "name": "v5.1.2", "date": "2026-06-01" }, { "name": "v5.1.3", "date": "2026-07-18" } ], "_stars": 62, "_contributors": [ { "user": "mattfidler", "count": 9452, "uuid": 514778 }, { "user": "billdenney", "count": 334, "uuid": 10359931 }, { "user": "wwang-at-github", "count": 68, "uuid": 13064566 }, { "user": "copilot", "count": 27, "uuid": 198982749 }, { "user": "hiddevandebeek", "count": 11, "uuid": 79250134 }, { "user": "daj025", "count": 7, "uuid": 13022669 }, { "user": "leovuong", "count": 4, "uuid": 92429953 }, { "user": "kestrel99", "count": 3, "uuid": 9568350 }, { "user": "eddelbuettel", "count": 2, "uuid": 673121 }, { "user": "hallowkm", "count": 2, "uuid": 9352362 }, { "user": "s0521", "count": 2, "uuid": 48432488 }, { "user": "claude", "count": 1, "uuid": 81847 }, { "user": "krlmlr", "count": 1, "uuid": 1741643 }, { "user": "timwaterhouse", "count": 1, "uuid": 19149867 } ], "_userbio": { "uuid": 94710774, "type": "organization", "name": "nlmixr2", "followers": 57 }, "_downloads": { "count": 2751, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/rxode2" }, "_devurl": "https://github.com/nlmixr2/rxode2", "_pkgdown": "https://nlmixr2.github.io/rxode2/", "_searchresults": 1984, "_topics": [ "openblas", "onetbb", "cpp", "openmp" ], "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/NEWS.html", "extra/NEWS.txt", "extra/readme.html", "extra/readme.md", "extra/rxode2.html", "manual.pdf" ], "_homeurl": "https://github.com/nlmixr2/rxode2", "_realowner": "nlmixr2", "_cranurl": true, "_releases": [ { "version": "2.0.6", "date": "2022-05-09" }, { "version": "2.0.7", "date": "2022-05-17" }, { "version": "2.0.8", "date": "2022-09-23" }, { "version": "2.0.9", "date": "2022-10-19" }, { "version": "2.0.10", "date": "2022-10-20" }, { "version": "2.0.11", "date": "2022-11-01" }, { "version": "2.0.12", "date": "2023-03-28" }, { "version": "2.0.13", "date": "2023-04-22" }, { "version": "2.0.14", "date": "2023-10-07" }, { "version": "2.1.0", "date": "2023-12-12" }, { "version": "2.1.1", "date": "2023-12-13" }, { "version": "2.1.2", "date": "2024-01-31" }, { "version": "2.1.3", "date": "2024-05-28" }, { "version": "3.0.0", "date": "2024-09-18" }, { "version": "3.0.1", "date": "2024-09-22" }, { "version": "3.0.2", "date": "2024-10-30" }, { "version": "3.0.3", "date": "2024-12-15" }, { "version": "3.0.4", "date": "2025-02-14" }, { "version": "4.0.0", "date": "2025-07-16" }, { "version": "4.0.1", "date": "2025-07-18" }, { "version": "4.0.2", "date": "2025-07-21" }, { "version": "4.0.3", "date": "2025-07-24" }, { "version": "4.1.0", "date": "2025-08-29" }, { "version": "4.1.1", "date": "2025-10-08" }, { "version": "5.0.0", "date": "2025-11-28" }, { "version": "5.0.1", "date": "2025-12-11" }, { "version": "5.0.2", "date": "2026-03-20" }, { "version": "5.1.1", "date": "2026-05-28" }, { "version": "5.1.2", "date": "2026-06-02" }, { "version": "5.1.3", "date": "2026-07-19" }, { "version": "5.1.4", "date": "2026-07-20" } ], "_exports": [ ".assertRenameErrorModelLine", ".cbindOme", ".clearPipe", ".collectWarnings", ".convertId", ".copyUi", ".expandPars", ".extraC", ".extraCnow", ".getErrDist", ".getLastIdLvl", ".getNamedArgumentsToPredDf", ".getWh", ".handleSingleErrTypeNormOrTFoceiBase", ".iniGetAppendArg", ".iniHandleFixOrUnfix", ".iniHandleLine", ".malert", ".matchesLangTemplate", ".minfo", ".modelHandleModelLines", ".msuccess", ".mwarn", ".pipeDfObs", ".pipeDfSub", ".pipeEvents", ".pipeInits", ".pipeKeep", ".pipeNStud", ".pipeNSub", ".pipeOmega", ".pipeParams", ".pipeRx", ".pipeSigma", ".pipeThetaMat", ".quoteCallInfoLines", ".rstudioComplete", ".rxAdjoint", ".rxAdjointExpand", ".rxAdjointGrad", ".rxAdjointGradBuild", ".rxAdjointGradEval", ".rxAdjointGradEvalC", ".rxAdjointGradPop", ".rxAdjointMethodStiff", ".rxAdjointModel", ".rxAdjointSolve", ".rxAdjointSolveBuild", ".rxAdjointSolveEvalC", ".rxBlankIni", ".rxC", ".rxDelaySensJump", ".rxDelaySensJumpEvents", ".rxDelaySensJumpMap", ".rxDelaySensJumpMapCached", ".rxDiscreteAdjointBuild", ".rxDiscreteAdjointGrad", ".rxDiscreteForwardSens", ".rxDocTable", ".rxFromSE", ".rxGetHiBoundaryPred1AndIni", ".rxGetLambdaFromPred1AndIni", ".rxGetLowBoundaryPred1AndIni", ".rxGetPredictionDVTransform", ".rxGetPredictionF", ".rxGetPredictionFTransform", ".rxGetSeed", ".rxGetVarianceForErrorType", ".rxInjectMatExpOdes", ".rxIsLinCmt", ".rxJacobian", ".rxLastCompileSuccess", ".rxLinCmt", ".rxLinCmtGen", ".rxLinNcmt", ".rxMemoisedFns", ".rxode2ptrs", ".rxPastBaseLinesFromEnv", ".rxPrune", ".rxRename", ".rxSEeqUsr", ".rxSens", ".rxSetSeed", ".rxToSE", ".rxTransform", ".rxTransInfo", ".rxWithOptions", ".rxWithSink", ".rxWithSinkBoth", ".rxWithWd", ".s3register", ".solComp2", ".solComp3", ".symengineFs", ".toClassicEvid", ".udfCallFunArg", ".udfEnvReset", ".udfEnvSet", ".udfEnvSetUdf", ".udfExists", ".udfMd5Info", ".uiArg", ".useUtf", ".vecDf", "add.dosing", "add.sampling", "aes", "as_tibble.rxEt", "as.arrow", "as.et", "as.ini", "as.model", "as.rxEvid", "as.rxRateDur", "as.rxUi", "assertCompartmentExists", "assertCompartmentName", "assertCompartmentNew", "assertExists", "assertIniDf", "assertParameterValue", "assertRxLinCmt", "assertRxUi", "assertRxUiEstimatedResiduals", "assertRxUiIovNoCor", "assertRxUiMixedOnly", "assertRxUiMuRefOnly", "assertRxUiNoAutoregressive", "assertRxUiNoMix", "assertRxUiNormal", "assertRxUiPopulationOnly", "assertRxUiPrediction", "assertRxUiRandomOnIdOnly", "assertRxUiSingleEndpoint", "assertRxUiTransformNormal", "assertRxUnbounded", "assertVariableExists", "assertVariableName", "assertVariableNew", "binomProbs", "bolus", "boxCox", "boxCoxInv", "cvPost", "d2aELU", "d2ELU", "d2ELUa", "d2GELU", "d3GELU", "d4GELU", "delay", "dELU", "dELUa", "dfWishart", "dGELU", "dlReLU", "dmexpit", "dPReLU", "dPReLUa", "dPReLUa1", "dReLU", "dSELU", "dsoftplus", "dSwish", "ELU", "erf", "et", "etExpand", "etRbind", "etRep", "etSeq", "etTrans", "eventTable", "evid_", "expand_limits", "expit", "facet_wrap", "findLhs", "forderForceBase", "gammap", "gammapDer", "gammapInv", "gammapInva", "gammaq", "gammaqInv", "gammaqInva", "GELU", "genShinyApp.template", "geom_amt", "geom_cens", "geom_line", "getBaseIniSimModel", "getBaseSimModel", "getBaseSymengineModel", "getRxThreads", "ggplot", "guide_none", "indLin", "infuse", "infuseDur", "ini", "ini<-", "invWR1d", "is.rxEt", "is.rxSolve", "is.rxStackData", "label_both", "label_context", "label_value", "label_wrap_gen", "linMod", "linMod0", "linModA0", "linModB", "linModB0", "linModD", "linModD0", "linModM", "linModM0", "linToOde", "llikBeta", "llikBinom", "llikCauchy", "llikChisq", "llikExp", "llikF", "llikGamma", "llikGeom", "llikNbinom", "llikNbinomMu", "llikNorm", "llikPois", "llikT", "llikUnif", "llikWeibull", "logit", "logitNormInfo", "lotri", "lowergamma", "lReLU", "meanProbs", "mexpit", "mix", "mlogit", "model", "model<-", "modelExtract", "obs", "odeMethodToInt", "odeToLin", "phantom", "phi", "PReLU", "probit", "probitInv", "probitNormInfo", "ReLU", "rinvchisq", "rLKJ1", "rxAllowUnload", "rxAppendModel", "rxAssignControlValue", "rxAssignPtr", "rxbeta", "rxbinom", "rxBlockZeros", "rxC", "rxCat", "rxcauchy", "rxCbindStudyIndividual", "rxChain", "rxChain2", "rxchisq", "rxClean", "rxCombineErrorLines", "rxCompile", "rxCondition", "rxControl", "rxControlUpdateSens", "rxCores", "rxCreateCache", "rxD", "rxDelete", "rxDemoteAddErr", "rxDerived", "rxDeserialize", "rxDfdy", "rxDll", "rxDllLoaded", "rxDynLoad", "rxDynUnload", "rxErrTypeCombine", "rxEtDispatchSolve", "rxEventSensDeactivate", "rxEventSensLoadModel", "rxEventTableFile", "rxEvid", "rxexp", "rxExpandFEta_", "rxExpandGrid", "rxExpandGrid_", "rxExpandIfElse", "rxExpandSens_", "rxExpandSens2_", "rxExpandSens3_", "rxf", "rxFixPop", "rxFixRes", "rxForget", "rxFromSE", "rxFun", "rxFunParse", "rxgamma", "rxgeom", "rxGetControl", "rxGetDefaultSerialize", "rxGetDistributionSimulationLines", "rxGetLin", "rxGetModel", "rxGetrxode2", "rxGetSeed", "rxGetSerialType_", "rxHasAr", "rxHtml", "rxIndLinState", "rxIndLinStrategy", "rxInit", "rxInits", "rxIntToBase", "rxIntToLetter", "rxInv", "rxIs", "rxIsAutoSwitch", "rxIsCurrent", "rxIsDense", "rxIsImplicit", "rxIsLoaded", "rxIsNonStiff", "rxIsStiff", "rxLastCompile", "rxLhs", "rxLoad", "rxLoadState", "rxLock", "rxMd5", "rxMemoryEstimate", "rxMemSummary", "rxModels_", "rxModelVars", "rxModelVarsS3", "rxnbinom", "rxnbinomMu", "rxnorm", "rxNorm", "rxnormV", "rxNumLoaded", "rxode", "RxODE", "rxode<-", "RxODE<-", "rxode2", "rxode2<-", "rxode2parse", "rxode2parseAssignPackagesToLoad", "rxode2parseAssignPointerTranslation", "rxode2parseAssignTranslation", "rxode2parseD", "rxode2parseGetPackagesToLoad", "rxode2parseGetPointerAssignment", "rxode2parseGetTranslation", "rxOdeToIndLin", "rxOldQsDes", "rxOmegaVarCovDeriv", "rxOmegaVarCovDeriv_", "rxOptExpr", "rxord", "rxParam", "rxParams", "rxParseErr", "rxParsePk", "rxParsePred", "rxParseSetSilentErr", "rxParseSuppressMsg", "rxPkg", "rxpois", "rxPp", "rxPreferredDistributionName", "rxProgress", "rxProgressAbort", "rxProgressStop", "rxPrune", "rxRateDur", "rxRawToC", "rxReload", "rxRemoveControl", "rxRename", "rxRepR0_", "rxReq", "rxRmFun", "rxRmFunParse", "rxRmvn", "rxS", "rxSaveState", "rxSeedEng", "rxSensMatExp", "rxSerialize", "rxSetControl", "rxSetCovariateNamesForPiping", "rxSetIni0", "rxSetPipingAuto", "rxSetProd", "rxSetProgressBar", "rxSetSeed", "rxSetSilentErr", "rxSetSum", "rxSetupIni", "rxSetupScale", "rxShiny", "rxSimThetaOmega", "rxSolve", "rxSolveAdjoint", "rxSolveAdjointRk4", "rxSolveChunked", "rxSolveFree", "rxSolveSetup", "rxSplitPlusQ", "rxStack", "rxState", "rxStateOde", "rxSumProdModel", "rxSupportedFuns", "rxSuppressMsg", "rxSymInvChol", "rxSymInvCholCreate", "rxSymInvCholN", "rxSyncOptions", "rxt", "rxTempDir", "rxTest", "rxTheme", "rxTick", "rxToIndLin", "rxToSE", "rxTrans", "rxUdfUi", "rxUdfUiControl", "rxUdfUiData", "rxUdfUiEst", "rxUdfUiExpr", "rxUdfUiFlag", "rxUdfUiIniDf", "rxUdfUiIniLhs", "rxUdfUiIsValue", "rxUdfUiMv", "rxUdfUiNum", "rxUdfUiParsing", "rxUdfUiReset", "rxUiCompress", "rxUiDecompress", "rxUiDeparse", "rxUiDevelop", "rxUiGet", "rxunif", "rxUnload", "rxUnloadAll", "rxUnlock", "rxUse", "rxValidate", "rxVersion", "rxweibull", "rxWithPreserveSeed", "rxWithSeed", "scale_type", "scale_x_continuous", "scale_x_date", "scale_x_discrete", "scale_y_continuous", "scale_y_date", "scale_y_discrete", "SELU", "setCvodeLinearSolver", "setRxThreads", "softplus", "splitBolus", "stat_amt", "stat_cens", "swapMatListWithCube", "Swish", "testCompartmentExists", "testExists", "testIniDf", "testRxLinCmt", "testRxUnbounded", "testVariableExists", "toTrialDuration", "uppergamma", "waiver", "warnRxBounded", "write.template.server", "write.template.ui", "xlab", "yeoJohnson", "yeoJohnsonInv", "ylab", "zeroRe" ], "_datasets": [ { "name": "rxReservedKeywords", "title": "A list and description of rxode2 supported reserved keywords", "object": "rxReservedKeywords", "class": [ "data.frame" ], "fields": [ "Reserved Name", "Meaning", "Alias" ], "rows": 31, "table": true, "tojson": true }, { "name": "rxResidualError", "title": "A description of Rode2 supported residual errors", "object": "rxResidualError", "class": [ "data.frame" ], "fields": [ "Error model", "Functional Form", "Transformation", "code", "addProp", "lhs" ], "rows": 183, "table": true, "tojson": true }, { "name": "rxSyntaxFunctions", "title": "A list and description of Rode supported syntax functions", "object": "rxSyntaxFunctions", "class": [ "data.frame" ], "fields": [ "Function", "Description", "Aliases" ], "rows": 106, "table": true, "tojson": true } ], "_help": [ { "page": "dot-cbindOme", "title": "cbind Ome", "topics": [ ".cbindOme" ] }, { "page": "dot-collectWarnings", "title": "Collect warnings and just warn once.", "topics": [ ".collectWarnings" ] }, { "page": "dot-copyUi", "title": "This copies the rxode2 UI object so it can be modified", "topics": [ ".copyUi" ] }, { "page": "dot-handleSingleErrTypeNormOrTFoceiBase", "title": "Handle the single error for normal or t distributions", "topics": [ ".handleSingleErrTypeNormOrTFoceiBase" ] }, { "page": "dot-matchesLangTemplate", "title": "Check if a language object matches a template language object", "topics": [ ".matchesLangTemplate" ] }, { "page": "dot-modelHandleModelLines", "title": "Handle model lines", "topics": [ ".modelHandleModelLines" ] }, { "page": "dot-quoteCallInfoLines", "title": "Returns quoted call information", "topics": [ ".quoteCallInfoLines" ] }, { "page": "dot-rxLinCmtGen", "title": "Internal function to generate the model variables for a linCmt() model", "topics": [ ".rxLinCmtGen" ] }, { "page": "dot-rxode2ptrs", "title": "Get the rxode2 function pointers", "topics": [ ".rxode2ptrs" ] }, { "page": "dot-rxSensStrippable", "title": "Get model properties without compiling it.", "topics": [ ".rxSensStrippable" ] }, { "page": "dot-rxWithOptions", "title": "Temporarily set options then restore them while running code", "topics": [ ".rxWithOptions" ] }, { "page": "dot-rxWithWd", "title": "Temporarily set options then restore them while running code", "topics": [ ".rxWithWd" ] }, { "page": "dot-toClassicEvid", "title": "This converts NONMEM-style EVIDs to classic RxODE events", "topics": [ ".toClassicEvid" ] }, { "page": "dot-vecDf", "title": "Convert numeric vector to repeated data.frame", "topics": [ ".vecDf" ] }, { "page": "add.dosing", "title": "Add dosing to eventTable", "topics": [ "add.dosing" ] }, { "page": "add.sampling", "title": "Add sampling to eventTable", "topics": [ "add.sampling" ] }, { "page": "as_tibble.rxEt", "title": "Convert to tbl", "topics": [ "as_tibble.rxEt" ] }, { "page": "as.arrow", "title": "Convert an rxSolveOom result to a lazy Arrow Dataset", "topics": [ "as.arrow", "as.arrow.rxSolveOom" ] }, { "page": "as.data.table.rxEt", "title": "Convert an event table to a data.table", "topics": [ "as.data.table.rxEt" ] }, { "page": "as.et", "title": "Coerce object to data.frame", "topics": [ "as.et", "as.et.default" ] }, { "page": "as.ini", "title": "Turn into an ini block for initialization", "topics": [ "as.ini", "as.ini.call", "as.ini.character", "as.ini.data.frame", "as.ini.default", "as.ini.lotriFix", "as.ini.matrix" ] }, { "page": "as.model", "title": "Turn into a model expression", "topics": [ "as.model", "as.model.call", "as.model.character", "as.model.default", "as.model.list" ] }, { "page": "as.rxUi", "title": "As rxode2 ui", "topics": [ "as.rxUi", "as.rxUi.default", "as.rxUi.function", "as.rxUi.rxModelVars", "as.rxUi.rxode2", "as.rxUi.rxode2tos", "as.rxUi.rxUi" ] }, { "page": "assertCompartmentExists", "title": "Verify that the compartment exists in a model", "concept": [ "Assertions" ], "topics": [ "assertCompartmentExists", "testCompartmentExists" ] }, { "page": "assertCompartmentName", "title": "Verify that a value is a valid nlmixr2 compartment name", "concept": [ "Assertions" ], "topics": [ "assertCompartmentName", "assertExists", "assertParameterValue", "assertVariableName", "testExists" ] }, { "page": "assertCompartmentNew", "title": "Verify that a compartment would be new to the model", "concept": [ "Assertions" ], "topics": [ "assertCompartmentNew" ] }, { "page": "assertRxUi", "title": "Assert properties of the rxUi models", "concept": [ "Assertions" ], "topics": [ "assertRxUi", "assertRxUiEstimatedResiduals", "assertRxUiIovNoCor", "assertRxUiMixedOnly", "assertRxUiMuRefOnly", "assertRxUiNoAutoregressive", "assertRxUiNoMix", "assertRxUiNormal", "assertRxUiPopulationOnly", "assertRxUiPrediction", "assertRxUiRandomOnIdOnly", "assertRxUiSingleEndpoint", "assertRxUiTransformNormal" ] }, { "page": "assertVariableExists", "title": "Assert a variable exists in the model", "concept": [ "Assertions" ], "topics": [ "assertVariableExists", "testVariableExists" ] }, { "page": "assertVariableNew", "title": "Assert a variable would be new to the model", "concept": [ "Assertions" ], "topics": [ "assertVariableNew" ] }, { "page": "binomProbs", "title": "Calculate expected confidence bands with binomial sampling distribution", "topics": [ "binomProbs", "binomProbs.default" ] }, { "page": "bolus", "title": "Administer a bolus dose inside a rxode2 model", "topics": [ "bolus" ] }, { "page": "boxCox", "title": "boxCox/yeoJohnson and inverse boxCox/yeoJohnson functions", "topics": [ "boxCox", "boxCoxInv", "yeoJohnson", "yeoJohnsonInv" ] }, { "page": "coef.rxUi", "title": "Extract the initial coefficients from an rxode2 model (rxUi)", "topics": [ "coef.function", "coef.rxUi" ] }, { "page": "cvPost", "title": "Sample a covariance Matrix from the Posterior Inverse Wishart distribution.", "topics": [ "cvPost" ] }, { "page": "delay", "title": "Delayed state for delay differential equations", "topics": [ "delay" ] }, { "page": "dELU", "title": "Derivatives of the Exponential Linear Unit (ELU) Activation Function", "concept": [ "Activation Functions" ], "topics": [ "d2aELU", "d2ELU", "d2ELUa", "dELU", "dELUa" ] }, { "page": "dfWishart", "title": "This uses simulations to match the rse", "topics": [ "dfWishart" ] }, { "page": "dGELU", "title": "Derivatives of GELU", "concept": [ "Activation Functions" ], "topics": [ "d2GELU", "d3GELU", "d4GELU", "dGELU" ] }, { "page": "dlReLU", "title": "Derivative of Leaky ReLU activation function", "concept": [ "Activation Functions" ], "topics": [ "dlReLU" ] }, { "page": "dPReLU", "title": "Derivatives Parametric ReLU Activation Function", "concept": [ "Activation Functions" ], "topics": [ "dPReLU", "dPReLUa", "dPReLUa1" ] }, { "page": "dReLU", "title": "Derivative of the Rectified Linear Unit (ReLU) Activation Function", "concept": [ "Activation Functions" ], "topics": [ "dReLU" ] }, { "page": "dSELU", "title": "Derivative of the Scaled Exponential Linear Unit (SELU) Activation Function", "concept": [ "Activation Functions" ], "topics": [ "dSELU" ] }, { "page": "dsoftplus", "title": "Default Softplus Activation Function", "concept": [ "Activation Functions" ], "topics": [ "d2softplus", "d3softplus", "d4softplus", "dsoftplus" ] }, { "page": "dSwish", "title": "Derivative of the Swish Activation Function", "concept": [ "Activation Functions" ], "topics": [ "dSwish" ] }, { "page": "ELU", "title": "Exponential Linear Unit (ELU) Activation Function", "concept": [ "Activation Functions" ], "topics": [ "ELU" ] }, { "page": "erf", "title": "Error function", "topics": [ "erf" ] }, { "page": "et", "title": "Event Table Function", "topics": [ "et", "et.default", "et.function", "et.rxode2", "et.rxParams", "et.rxSolve", "et.rxUi" ] }, { "page": "etExpand", "title": "Expand additional doses", "topics": [ "etExpand" ] }, { "page": "etRbind", "title": "Combining event tables", "topics": [ "etRbind", "rbind.rxEt" ] }, { "page": "etRep", "title": "Repeat an rxode2 event table", "topics": [ "etRep", "rep.rxEt" ] }, { "page": "etSeq", "title": "Sequence of event tables", "topics": [ "etSeq", "seq.rxEt" ] }, { "page": "eventTable", "title": "Create an event table object", "concept": [ "Nonlinear regression", "Pharmacodynamics (PD)", "Pharmacokinetics (PK)", "ordinary differential equations" ], "topics": [ "eventTable" ] }, { "page": "evid_", "title": "Push a future dose or observation event from within an rxode2 model", "topics": [ "evid_" ] }, { "page": "gammap", "title": "Gammap: normalized lower incomplete gamma function", "topics": [ "gammap" ] }, { "page": "gammapDer", "title": "gammapDer: derivative of gammap", "topics": [ "gammapDer" ] }, { "page": "gammapInv", "title": "gammapInv and gammapInva: Inverses of normalized gammap function", "topics": [ "gammapInv", "gammapInva" ] }, { "page": "gammaq", "title": "Gammaq: normalized upper incomplete gamma function", "topics": [ "gammaq" ] }, { "page": "gammaqInv", "title": "gammaqInv and gammaqInva: Inverses of normalized gammaq function", "topics": [ "gammaqInv", "gammaqInva" ] }, { "page": "GELU", "title": "GELU activation function", "concept": [ "Activation Functions" ], "topics": [ "GELU" ] }, { "page": "genShinyApp.template", "title": "Generate an example (template) of a dosing regimen shiny app", "concept": [ "PK/PD", "pharmacometrics" ], "topics": [ "genShinyApp.template", "write.template.server", "write.template.ui" ] }, { "page": "getRxThreads", "title": "Get/Set the number of threads that rxode2 uses", "topics": [ "getRxThreads", "rxCores", "setRxThreads" ] }, { "page": "indLin", "title": "Transition ODEs written in d/dt() format to matrix exponential / inductive linearization format", "topics": [ "indLin", "rxOdeToIndLin", "rxToIndLin" ] }, { "page": "infuse", "title": "Administer a infusion (with rate being fixed) inside a rxode2 model", "topics": [ "infuse" ] }, { "page": "infuseDur", "title": "Administer a infusion (with duration being fixed) inside a rxode2 model", "topics": [ "infuseDur" ] }, { "page": "ini", "title": "Ini block for rxode2/nlmixr models", "concept": [ "Initial conditions" ], "topics": [ "ini", "ini.default", "ini.rxUi" ] }, { "page": "ini-set", "title": "Assign the ini block in the rxode2 related object", "topics": [ "ini<-" ] }, { "page": "is.rxEt", "title": "Check if object is an rxEt event table", "topics": [ "is.rxEt" ] }, { "page": "is.rxStackData", "title": "Return if the object can be stacked", "topics": [ "is.rxStackData" ] }, { "page": "linMod", "title": "Linear model to replace in rxode2 ui model", "concept": [ "User functions" ], "topics": [ "linMod", "linMod0", "linModA", "linModA0", "linModB", "linModB0", "linModD", "linModD0", "linModM", "linModM0" ] }, { "page": "linToOde", "title": "Convert linCmt rxUi models to ODE rxUi models", "topics": [ "linToOde" ] }, { "page": "llikBeta", "title": "Calculate the log likelihood of the binomial function (and its derivatives)", "topics": [ "llikBeta" ] }, { "page": "llikBinom", "title": "Calculate the log likelihood of the binomial function (and its derivatives)", "topics": [ "llikBinom" ] }, { "page": "llikCauchy", "title": "log likelihood of Cauchy distribution and it's derivatives (from stan)", "topics": [ "llikCauchy" ] }, { "page": "llikChisq", "title": "log likelihood and derivatives for chi-squared distribution", "topics": [ "llikChisq" ] }, { "page": "llikExp", "title": "log likelihood and derivatives for exponential distribution", "topics": [ "llikExp" ] }, { "page": "llikF", "title": "log likelihood and derivatives for F distribution", "topics": [ "llikF" ] }, { "page": "llikGamma", "title": "log likelihood and derivatives for Gamma distribution", "topics": [ "llikGamma" ] }, { "page": "llikGeom", "title": "log likelihood and derivatives for Geom distribution", "topics": [ "llikGeom" ] }, { "page": "llikNbinom", "title": "Calculate the log likelihood of the negative binomial function (and its derivatives)", "topics": [ "llikNbinom" ] }, { "page": "llikNbinomMu", "title": "Calculate the log likelihood of the negative binomial function (and its derivatives)", "topics": [ "llikNbinomMu" ] }, { "page": "llikNorm", "title": "Log likelihood for normal distribution", "topics": [ "llikNorm" ] }, { "page": "llikPois", "title": "log-likelihood for the Poisson distribution", "topics": [ "llikPois" ] }, { "page": "llikT", "title": "Log likelihood of T and it's derivatives (from stan)", "topics": [ "llikT" ] }, { "page": "llikUnif", "title": "log likelihood and derivatives for Unif distribution", "topics": [ "llikUnif" ] }, { "page": "llikWeibull", "title": "log likelihood and derivatives for Weibull distribution", "topics": [ "llikWeibull" ] }, { "page": "logit", "title": "logit and inverse logit (expit) functions", "topics": [ "expit", "logit", "logitNormInfo", "probitNormInfo" ] }, { "page": "lowergamma", "title": "lowergamma: upper incomplete gamma function", "topics": [ "lowergamma" ] }, { "page": "lReLU", "title": "Leaky ReLU activation function", "concept": [ "Activation Functions" ], "topics": [ "lReLU" ] }, { "page": "meanProbs", "title": "Calculate expected confidence bands or prediction intreval with normal or t sampling distribution", "topics": [ "meanProbs", "meanProbs.default" ] }, { "page": "mexpit", "title": "mexpit - Convert log-scale numbers to probabilities", "topics": [ "dmexpit", "mexpit" ] }, { "page": "mix", "title": "Specify a mixture model of variables", "topics": [ "mix" ] }, { "page": "mlogit", "title": "mlogit - Convert multiple probabilities to log-scale numbers", "topics": [ "mlogit" ] }, { "page": "model", "title": "Model block for rxode2/nlmixr models", "topics": [ "model", "model.default", "model.function", "model.rxModelVars", "model.rxode2", "model.rxUi" ] }, { "page": "model-set", "title": "Assign the model block in the rxode2 related object", "topics": [ "model<-" ] }, { "page": "modelExtract", "title": "Extract model lines from a rxui model", "topics": [ "modelExtract", "modelExtract.default", "modelExtract.function", "modelExtract.rxModelVars", "modelExtract.rxode2", "modelExtract.rxUi" ] }, { "page": "multiply", "title": "Multiply dose the rxode2 system in the model", "topics": [ "multiply" ] }, { "page": "obs", "title": "Add observations to a model", "topics": [ "obs" ] }, { "page": "odeMethodToInt", "title": "Conversion between character and integer ODE integration methods for rxode2", "topics": [ "odeMethodToInt" ] }, { "page": "odeToLin", "title": "Convert ODE-based linear compartment models to analytical linCmt() form", "topics": [ "odeToLin" ] }, { "page": "phantom", "title": "Administer a phantom/transit dose inside a rxode2 model", "topics": [ "phantom" ] }, { "page": "phi", "title": "Cumulative distribution of standard normal", "topics": [ "phi" ] }, { "page": "plot.rxSolve", "title": "Plot rxode2 objects", "concept": [ "rxode2 plotting" ], "topics": [ "plot.rxSolve", "plot.rxSolveConfint1", "plot.rxSolveConfint2" ] }, { "page": "PReLU", "title": "Parametric ReLU Activation Function", "concept": [ "Activation Functions" ], "topics": [ "PReLU" ] }, { "page": "print.rxModelVars", "title": "Print Values", "topics": [ "print.rxModelVars" ] }, { "page": "probit", "title": "probit and inverse probit functions", "topics": [ "probit", "probitInv" ] }, { "page": "ReLU", "title": "Rectified Linear Unit (ReLU) Activation Function", "concept": [ "Activation Functions" ], "topics": [ "ReLU" ] }, { "page": "replace", "title": "Replace dose the rxode2 system in the model", "topics": [ "replace" ] }, { "page": "reset", "title": "Reset the rxode2 system in the model", "topics": [ "reset" ] }, { "page": "rinvchisq", "title": "Scaled Inverse Chi Squared distribution", "topics": [ "rinvchisq" ] }, { "page": "rxAllowUnload", "title": "Allow unloading of dlls", "topics": [ "rxAllowUnload" ] }, { "page": "rxAppendModel", "title": "Append two rxui models together", "topics": [ "rxAppendModel" ] }, { "page": "rxAssignControlValue", "title": "Assign Control Variable", "topics": [ "rxAssignControlValue" ] }, { "page": "rxAssignPtr", "title": "Assign pointer based on model variables", "topics": [ "rxAssignPtr" ] }, { "page": "rxbeta", "title": "Simulate beta variable from threefry generator", "topics": [ "rxbeta" ] }, { "page": "rxbinom", "title": "Simulate Binomial variable from threefry generator", "topics": [ "rxbinom" ] }, { "page": "rxcauchy", "title": "Simulate Cauchy variable from threefry generator", "topics": [ "rxcauchy" ] }, { "page": "rxCbindStudyIndividual", "title": "Bind the study parameters and individual parameters", "topics": [ "rxCbindStudyIndividual" ] }, { "page": "rxchisq", "title": "Simulate chi-squared variable from threefry generator", "topics": [ "rxchisq" ] }, { "page": "rxClean", "title": "Cleanup anonymous DLLs by unloading them", "topics": [ "rxClean" ] }, { "page": "rxCompile", "title": "Compile a model if needed", "topics": [ "rxCompile", "rxCompile.character", "rxCompile.rxDll", "rxCompile.rxModelVars", "rxCompile.rxode2" ] }, { "page": "rxControlUpdateSens", "title": "This updates the tolerances based on the sensitivity equations", "topics": [ "rxControlUpdateSens" ] }, { "page": "rxCreateCache", "title": "This will create the cache directory for rxode2 to save between sessions", "topics": [ "rxCreateCache" ] }, { "page": "rxD", "title": "Add to rxode2's derivative tables", "topics": [ "rxD" ] }, { "page": "rxDelete", "title": "Delete the DLL for the model", "topics": [ "rxDelete" ] }, { "page": "rxDerived", "title": "Calculate derived parameters for the 1-, 2-, and 3- compartment linear models.", "topics": [ "rxDerived" ] }, { "page": "rxDfdy", "title": "Jacobian and parameter derivatives", "concept": [ "Query model information" ], "topics": [ "rxDfdy" ] }, { "page": "rxEtDispatchSolve", "title": "Dispatch solve to 'rxode2' solve", "topics": [ "rxEtDispatchSolve", "rxEtDispatchSolve.default" ] }, { "page": "rxEventTableFile", "title": "Create a file-backed event table reference", "topics": [ "rxEventTableFile" ] }, { "page": "rxEvid", "title": "EVID formatting for tibble and other places.", "topics": [ "as.character.rxEvid", "as.rxEvid", "c.rxEvid", "c.rxRateDur", "format.rxEvid", "format.rxRateDur", "print.rxEvid", "rxEvid", "units<-.rxEvid", "[.rxEvid", "[[.rxEvid" ] }, { "page": "rxexp", "title": "Simulate exponential variable from threefry generator", "topics": [ "rxexp" ] }, { "page": "rxf", "title": "Simulate F variable from threefry generator", "topics": [ "rxf" ] }, { "page": "rxFixPop", "title": "Apply the fixed population estimated parameters", "topics": [ "rxFixPop" ] }, { "page": "rxFixRes", "title": "Literally fix residual parameters", "topics": [ "rxFixRes" ] }, { "page": "rxFun", "title": "Add/Create C functions for use in rxode2", "topics": [ "rxFun", "rxRmFun" ] }, { "page": "rxgamma", "title": "Simulate gamma variable from threefry generator", "topics": [ "rxgamma" ] }, { "page": "rxgeom", "title": "Simulate geometric variable from threefry generator", "topics": [ "rxgeom" ] }, { "page": "rxGetControl", "title": "rxGetControl option from ui", "topics": [ "rxGetControl" ] }, { "page": "rxGetDefaultSerialize", "title": "Get the Default Serialization Type", "topics": [ "rxGetDefaultSerialize" ] }, { "page": "rxGetLin", "title": "Get the linear compartment model true function", "topics": [ "rxGetLin" ] }, { "page": "rxGetrxode2", "title": "Get rxode2 model from object", "topics": [ "rxGetrxode2" ] }, { "page": "rxGetSeed", "title": "Get the rxode2 seed", "topics": [ "rxGetSeed" ] }, { "page": "rxHasAr", "title": "Test if a model uses an autoregressive ('ar()') residual", "topics": [ "rxHasAr" ] }, { "page": "rxHtml", "title": "Format rxSolve and related objects as html.", "topics": [ "rxHtml", "rxHtml.rxSolve" ] }, { "page": "rxIndLinState", "title": "Set the preferred factoring by state", "topics": [ "rxIndLinState" ] }, { "page": "rxIndLinStrategy", "title": "This sets the inductive linearization strategy for matrix building", "topics": [ "rxIndLinStrategy" ] }, { "page": "rxIntToBase", "title": "Convert a positive base", "topics": [ "rxIntToBase" ] }, { "page": "rxIntToLetter", "title": "Convert a positive integer to a letter series", "topics": [ "rxIntToLetter" ] }, { "page": "rxInv", "title": "Invert matrix using RcppArmadillo.", "topics": [ "rxInv" ] }, { "page": "rxIsAutoSwitch", "title": "Check whether an ODE method string is an AutoSwitch composite pair", "topics": [ "rxIsAutoSwitch" ] }, { "page": "rxIsCurrent", "title": "Checks if the rxode2 object was built with the current build", "topics": [ "rxIsCurrent" ] }, { "page": "rxIsDense", "title": "Check whether an ODE solving method supports dense output", "topics": [ "rxIsDense" ] }, { "page": "rxIsImplicit", "title": "Check whether an ODE solving method requires a Jacobian (is implicit)", "topics": [ "rxIsImplicit" ] }, { "page": "rxIsNonStiff", "title": "Check whether an ODE solving method is a purely non-stiff solver", "topics": [ "rxIsNonStiff" ] }, { "page": "rxIsStiff", "title": "Check whether an ODE solving method is a purely stiff solver", "topics": [ "rxIsStiff" ] }, { "page": "rxLastCompile", "title": "Get the last compiled model information as alist", "topics": [ "rxLastCompile" ] }, { "page": "rxLhs", "title": "Left handed Variables", "concept": [ "Query model information" ], "topics": [ "rxLhs" ] }, { "page": "rxLock", "title": "Lock/unlocking of rxode2 dll file", "topics": [ "rxLock", "rxUnlock" ] }, { "page": "rxMemoryEstimate", "title": "Estimate memory required by rxSolve() for a given dataset and model", "topics": [ "rxMemoryEstimate" ] }, { "page": "rxMemSummary", "title": "Create a per-ID event summary for memory estimation", "topics": [ "rxMemSummary" ] }, { "page": "rxnbinom", "title": "Simulate Binomial variable from threefry generator", "topics": [ "rxnbinom", "rxnbinomMu" ] }, { "page": "rxNorm", "title": "Get the normalized model", "topics": [ "rxNorm" ] }, { "page": "rxnormV", "title": "Simulate random normal variable from threefry generator", "topics": [ "rxnorm", "rxnormV" ] }, { "page": "rxNumLoaded", "title": "Get the number of loaded rxode2 DLLs", "topics": [ "rxNumLoaded" ] }, { "page": "rxode2", "title": "Create an ODE-based model specification", "concept": [ "Nonlinear regression", "ODE models", "Ordinary differential equations", "Pharmacodynamics (PD)", "Pharmacokinetics (PK)" ], "topics": [ "RxODE", "rxode", "rxode2" ] }, { "page": "rxode2-set", "title": "Set the function body of an rxUi object while retaining other object information (like data)", "topics": [ "rxode2<-", "rxode2<-.default", "rxode2<-.function", "RxODE<-", "rxode<-" ] }, { "page": "rxode2parse", "title": "Internal translation to get model variables list", "topics": [ "rxode2parse" ] }, { "page": "rxode2parseAssignTranslation", "title": "This assigns the c level linkages for a roxde2 model", "topics": [ "rxode2parseAssignTranslation" ] }, { "page": "rxode2parseD", "title": "This gives the derivative table for rxode2", "topics": [ "rxode2parseD" ] }, { "page": "rxode2parseAssignPackagesToLoad", "title": "Control the packages that are loaded when a 'rxode2' model dll is loaded", "topics": [ "rxode2parseAssignPackagesToLoad", "rxode2parseGetPackagesToLoad" ] }, { "page": "rxode2parseGetPointerAssignment", "title": "This function gets the currently assigned function pointer assignments", "topics": [ "rxode2parseGetPointerAssignment" ] }, { "page": "rxode2parseGetTranslation", "title": "This function gets the currently assigned translations", "topics": [ "rxode2parseGetTranslation" ] }, { "page": "rxOmegaVarCovDeriv", "title": "Variance-covariance (non-Cholesky) Omega parameterization derivatives", "topics": [ "rxOmegaVarCovDeriv" ] }, { "page": "rxOptExpr", "title": "Optimize rxode2 for computer evaluation", "topics": [ "rxOptExpr" ] }, { "page": "rxord", "title": "Simulate ordinal value", "topics": [ "rxord" ] }, { "page": "rxParams", "title": "Parameters specified by the model", "concept": [ "Query model information" ], "topics": [ "rxParam", "rxParams", "rxParams.rxEt", "rxParams.rxode2", "rxParams.rxSolve" ] }, { "page": "rxParseSuppressMsg", "title": "Respect suppress messages", "topics": [ "rxParseSuppressMsg" ] }, { "page": "rxPkg", "title": "Creates a package from compiled rxode2 models", "topics": [ "rxPkg" ] }, { "page": "rxpois", "title": "Simulate random Poisson variable from threefry generator", "topics": [ "rxpois" ] }, { "page": "rxPp", "title": "Simulate a from a Poisson process", "topics": [ "rxPp" ] }, { "page": "rxPreferredDistributionName", "title": "Change distribution name to the preferred distribution name term", "topics": [ "rxPreferredDistributionName" ] }, { "page": "rxProgress", "title": "rxode2 progress bar functions", "topics": [ "rxProgress", "rxProgressAbort", "rxProgressStop", "rxTick" ] }, { "page": "rxRateDur", "title": "Creates a rxRateDur object", "topics": [ "as.character.rxRateDur", "as.rxRateDur", "rxRateDur", "[.rxRateDur", "[[.rxRateDur" ] }, { "page": "rxRemoveControl", "title": "rxRemoveControl options for UI object", "topics": [ "rxRemoveControl" ] }, { "page": "rxRename", "title": "Rename items inside of a 'rxode2' ui model", "topics": [ ".rxRename", "rename.function", "rename.rxUi", "rxRename", "rxRename.default", "rxRename.function", "rxRename.rxUi" ] }, { "page": "rxReservedKeywords", "title": "A list and description of rxode2 supported reserved keywords", "topics": [ "rxReservedKeywords" ] }, { "page": "rxResidualError", "title": "A description of Rode2 supported residual errors", "topics": [ "rxResidualError" ] }, { "page": "rxRmvn", "title": "Simulate from a (truncated) multivariate normal", "topics": [ "rxRmvn" ] }, { "page": "rxS", "title": "Load a model into a symengine environment", "topics": [ "rxS" ] }, { "page": "rxSensMatExp", "title": "Differentiate and expand a matrix exponential model with forward sensitivities", "topics": [ "rxSensMatExp" ] }, { "page": "rxSetControl", "title": "rxSetControl options for UI object", "topics": [ "rxSetControl" ] }, { "page": "rxSetCovariateNamesForPiping", "title": "Assign covariates for piping", "topics": [ "rxSetCovariateNamesForPiping" ] }, { "page": "rxSetIni0", "title": "Set Initial conditions to time zero instead of the first observed/dosed time", "topics": [ "rxSetIni0" ] }, { "page": "rxSetPipingAuto", "title": "Set the variables for the model piping automatic covarite selection", "topics": [ "rxSetPipingAuto" ] }, { "page": "rxSetProd", "title": "Defunct setting of product", "topics": [ "rxSetProd" ] }, { "page": "rxSetProgressBar", "title": "Set timing for progress bar", "topics": [ "rxSetProgressBar" ] }, { "page": "rxSetSeed", "title": "Set the parallel seed for rxode2 random number generation", "topics": [ "rxSetSeed" ] }, { "page": "rxSetSum", "title": "Defunct setting of sum", "topics": [ "rxSetSum" ] }, { "page": "rxShiny", "title": "Use Shiny to help develop an rxode2 model", "topics": [ "rxShiny", "rxShiny.default", "rxShiny.rxSolve" ] }, { "page": "rxSimThetaOmega", "title": "Simulate Parameters from a Theta/Omega specification", "topics": [ "rxSimThetaOmega" ] }, { "page": "rxSolve", "title": "Options, Solving & Simulation of an ODE/solved system", "topics": [ "predict.function", "predict.rxEt", "predict.rxode2", "predict.rxParams", "predict.rxSolve", "predict.rxUi", "rxControl", "rxSolve", "rxSolve.default", "rxSolve.function", "rxSolve.nlmixr2FitCore", "rxSolve.nlmixr2FitData", "rxSolve.rxode2tos", "rxSolve.rxSolve", "rxSolve.rxUi", "simulate.rxode2", "simulate.rxParams", "simulate.rxSolve", "solve.function", "solve.rxEt", "solve.rxode2", "solve.rxParams", "solve.rxSolve", "solve.rxUi", "update.rxSolve" ] }, { "page": "rxSolveAdjoint", "title": "Solve a model with adjoint (backward) sensitivities, drop-in for forward sens", "topics": [ "rxSolveAdjoint" ] }, { "page": "rxSolveAdjointRk4", "title": "Solve a model with an in-engine discrete-adjoint ('s') method", "topics": [ "rxSolveAdjointRk4" ] }, { "page": "rxSolveChunked", "title": "Solve an ODE model in memory-safe chunks", "topics": [ "rxSolveChunked" ] }, { "page": "rxStack", "title": "Stack a solved object for things like default ggplot2 plot", "topics": [ "rxStack" ] }, { "page": "rxState", "title": "State variables", "concept": [ "Query model information" ], "topics": [ "rxState" ] }, { "page": "rxStateOde", "title": "Get the ODE states only", "topics": [ "rxStateOde" ] }, { "page": "rxSumProdModel", "title": "Recast model in terms of sum/prod", "topics": [ "rxSumProdModel" ] }, { "page": "rxSupportedFuns", "title": "Get list of supported functions", "topics": [ "rxSupportedFuns" ] }, { "page": "rxSuppressMsg", "title": "Respect suppress messages", "topics": [ "rxSuppressMsg" ] }, { "page": "rxSymInvChol", "title": "Get Omega^-1 and derivatives", "topics": [ "rxSymInvChol" ] }, { "page": "rxSyncOptions", "title": "Sync options with rxode2 variables", "topics": [ "rxSyncOptions" ] }, { "page": "rxSyntaxFunctions", "title": "A list and description of Rode supported syntax functions", "topics": [ "rxSyntaxFunctions" ] }, { "page": "rxt", "title": "Simulate student t variable from threefry generator", "topics": [ "rxt" ] }, { "page": "rxTempDir", "title": "Get the rxode2 temporary directory", "topics": [ "rxTempDir" ] }, { "page": "rxTheme", "title": "rxTheme is the ggplot2 theme for rxode2 plots", "concept": [ "rxode2 plotting" ], "topics": [ "rxTheme" ] }, { "page": "rxToSE", "title": "rxode2 to symengine environment", "topics": [ ".rxFromSE", ".rxToSE", "rxFromSE", "rxToSE" ] }, { "page": "rxTrans", "title": "Translate the model to C code if needed", "topics": [ "rxTrans", "rxTrans.character", "rxTrans.default" ] }, { "page": "rxUdfUiControl", "title": "Return the control that is being processed or setup control for processing", "concept": [ "User functions" ], "topics": [ "rxUdfUiControl" ] }, { "page": "rxUdfUiData", "title": "Return the data.frame that is being processed or setup data.frame for processing", "concept": [ "User functions" ], "topics": [ "rxUdfUiData" ] }, { "page": "rxUdfUiEst", "title": "Return the current estimation method for the UI processing", "concept": [ "User functions" ], "topics": [ "rxUdfUiEst" ] }, { "page": "rxUdfUiExpr", "title": "Give the expression as a compressed model or expression", "topics": [ "rxUdfUiExpr" ] }, { "page": "rxUdfUiFlag", "title": "Is the expression actually a flag that can be used in the rxUdfUi functions?", "topics": [ "rxUdfUiFlag" ] }, { "page": "rxUdfUiIniDf", "title": "Get the rxode2 iniDf of the current UI being processed (or return NULL)", "topics": [ "rxUdfUiIniDf" ] }, { "page": "rxUdfUiIniLhs", "title": "Return the lhs parsed language expression", "concept": [ "User functions" ], "topics": [ "rxUdfUiIniLhs" ] }, { "page": "rxUdfUiIsValue", "title": "Is the expression actually equal to a value?", "topics": [ "rxUdfUiIsValue" ] }, { "page": "rxUdfUiMv", "title": "Return the model variables that is being processed or setup model variables for processing", "concept": [ "User functions" ], "topics": [ "rxUdfUiMv" ] }, { "page": "rxUdfUiNum", "title": "This gives the current number in the ui of the particular function being called.", "concept": [ "User functions" ], "topics": [ "rxUdfUiNum" ] }, { "page": "rxUdfUiParsing", "title": "Returns if the current ui function is being parsed", "concept": [ "User functions" ], "topics": [ "rxUdfUiParsing" ] }, { "page": "rxUiDecompress", "title": "Compress/Decompress 'rxode2' ui", "topics": [ "rxUiCompress", "rxUiDecompress" ] }, { "page": "rxUiDeparse", "title": "This is a generic function for deparsing certain objects when printing out a rxode2 object. Currently it is used for any meta-information", "topics": [ "rxUiDeparse", "rxUiDeparse.default", "rxUiDeparse.lotriFix", "rxUiDeparse.rxControl" ] }, { "page": "rxUiDevelop", "title": "rxUiDevelop - Enable/Disable rxUi development. Here all $ completions are given", "topics": [ "rxUiDevelop" ] }, { "page": "rxUiGet", "title": "S3 for getting information from UI model", "topics": [ "rxUiGet", "rxUiGet.allCovs", "rxUiGet.cmtLines", "rxUiGet.covLhs", "rxUiGet.default", "rxUiGet.dvidLine", "rxUiGet.etaLhs", "rxUiGet.fun", "rxUiGet.funPartsDigest", "rxUiGet.funPrint", "rxUiGet.funTxt", "rxUiGet.ini", "rxUiGet.iniFun", "rxUiGet.interpLines", "rxUiGet.levelLhs", "rxUiGet.levels", "rxUiGet.lhsCov", "rxUiGet.lhsEta", "rxUiGet.lhsTheta", "rxUiGet.lhsVar", "rxUiGet.lstChr", "rxUiGet.md5", "rxUiGet.model", "rxUiGet.modelDesc", "rxUiGet.modelFun", "rxUiGet.multipleEndpoint", "rxUiGet.muRefTable", "rxUiGet.omega", "rxUiGet.paramsLine", "rxUiGet.props", "rxUiGet.sha1", "rxUiGet.simulationIniModel", "rxUiGet.simulationModel", "rxUiGet.simulationSigma", "rxUiGet.splitDose", "rxUiGet.splitDoseLines", "rxUiGet.state", "rxUiGet.stateDf", "rxUiGet.statePropDf", "rxUiGet.symengineModelNoPrune", "rxUiGet.symengineModelPrune", "rxUiGet.theta", "rxUiGet.thetaLhs", "rxUiGet.thetaLower", "rxUiGet.thetaUpper", "rxUiGet.varLhs" ] }, { "page": "rxunif", "title": "Simulate uniform variable from threefry generator", "topics": [ "rxunif" ] }, { "page": "rxUnloadAll", "title": "Unloads all rxode2 compiled DLLs", "topics": [ "rxUnloadAll" ] }, { "page": "rxUse", "title": "Use model object in your package", "topics": [ "rxUse" ] }, { "page": "rxValidate", "title": "Validate rxode2 This allows easy validation/qualification of nlmixr by running the testing suite on your system.", "topics": [ "rxTest", "rxValidate" ] }, { "page": "rxweibull", "title": "Simulate Weibull variable from threefry generator", "topics": [ "rxweibull" ] }, { "page": "rxWithSeed", "title": "Preserved seed and possibly set the seed", "topics": [ "rxWithPreserveSeed", "rxWithSeed" ] }, { "page": "SELU", "title": "Scaled Exponential Linear Unit (SELU) Activation Function", "concept": [ "Activation Functions" ], "topics": [ "SELU" ] }, { "page": "softplus", "title": "Softplus Activation Function", "concept": [ "Activation Functions" ], "topics": [ "softplus" ] }, { "page": "splitBolus", "title": "Split bolus doses across compartments inside an rxode2 model", "topics": [ "splitBolus" ] }, { "page": "stat_amt", "title": "Dosing/Amt geom/stat", "topics": [ "geom_amt", "stat_amt" ] }, { "page": "stat_cens", "title": "Censoring geom/stat", "topics": [ "geom_cens", "stat_cens" ] }, { "page": "summary.rxode2", "title": "Print expanded information about the rxode2 object.", "topics": [ "summary.rxode2" ] }, { "page": "swapMatListWithCube", "title": "Swaps the matrix list with a cube", "topics": [ "swapMatListWithCube" ] }, { "page": "Swish", "title": "Switch Activation Function", "concept": [ "Activation Functions" ], "topics": [ "Swish" ] }, { "page": "testIniDf", "title": "This function tests if this object is a iniDf as needed by the UI", "concept": [ "Assertions" ], "topics": [ "assertIniDf", "testIniDf" ] }, { "page": "testRxLinCmt", "title": "Test if rxode2 uses linear solved systems", "topics": [ "assertRxLinCmt", "testRxLinCmt" ] }, { "page": "testRxUnbounded", "title": "Test if the rxode2 model has any parameters with user defined boundaries", "concept": [ "Assertions" ], "topics": [ "assertRxUnbounded", "testRxUnbounded", "warnRxBounded" ] }, { "page": "toTrialDuration", "title": "Convert event data to trial duration data A helper function to create a custom event table. The observation time will start from the first event time (baseline) and end at trial duration. The interval is the spacing between each observation.", "topics": [ "toTrialDuration" ] }, { "page": "update.rxUi", "title": "Update for rxUi", "topics": [ "update.rxUi" ] }, { "page": "uppergamma", "title": "uppergamma: upper incomplete gamma function", "topics": [ "uppergamma" ] }, { "page": "zeroRe", "title": "Set random effects and residual error to zero", "concept": [ "Initial conditions" ], "topics": [ "zeroRe" ] } ], "_pkglogo": "https://github.com/nlmixr2/rxode2/raw/HEAD/logo.png", "_readme": "https://github.com/nlmixr2/rxode2/raw/HEAD/README.md", "_rundeps": [ "armadillo4r", "backports", "BH", "cachem", "checkmate", "cli", "cpp11", "cpp4r", "crayon", "data.table", "digest", "dparser", "farver", "fastmap", "ggplot2", "glue", "gtable", "inline", "isoband", "labeling", "lifecycle", "lotri", "memoise", "mirai", "nanonext", "PreciseSums", "R6", "RColorBrewer", "Rcpp", "RcppArmadillo", "RcppEigen", "RcppParallel", "rex", "rlang", "rxode2ll", "S7", "scales", "sitmo", "StanHeaders", "sys", "vctrs", "viridisLite", "withr" ], "_sysdeps": [ { "shlib": "liblapack", "package": "libopenblas0-pthread", "source": "openblas", "version": "0.3.32+ds-5", "name": "openblas", "homepage": "https://www.openblas.net/", "description": "Optimized BLAS (linear algebra) library (shared lib, pthread)" }, { "shlib": "libblas", "package": "libopenblas0-pthread", "source": "openblas", "version": "0.3.32+ds-5", "name": "openblas", "homepage": "https://www.openblas.net/", "description": "Optimized BLAS (linear algebra) library (shared lib, pthread)" }, { "shlib": "libtbb", "package": "libtbb12", "headers": "libtbb-dev", "source": "onetbb", "version": "2022.3.0-2", "name": "onetbb", "homepage": "https://uxlfoundation.github.io/oneTBB/", "description": "parallelism library for C++ - runtime files" }, { "shlib": "libstdc++", "package": "libstdc++6", "source": "gcc", "version": "16-20260322-1ubuntu1", "name": "c++", "homepage": "http://gcc.gnu.org/", "description": "GNU Standard C++ Library v3" }, { "shlib": "libgomp", "package": "libgomp1", "source": "gcc", "version": "16-20260322-1ubuntu1", "name": "openmp", "homepage": "http://gcc.gnu.org/", "description": "GCC OpenMP (GOMP) support library" } ], "_vignettes": [ { "source": "rxode2-syntax.Rmd", "filename": "rxode2-syntax.html", "title": "rxode2 ODE solving syntax", "engine": "knitr::rmarkdown_notangle", "headings": [ "Introduction", "Creating rxode2 models", "Syntax", "Note", "Example model", "Example", "Interface and data handling between R and the generated C code" ], "created": "2021-12-01 07:08:21", "modified": "2026-04-28 22:17:08", "commits": 7 } ], "_score": 12.710996016741179, "_indexed": true, "_nocasepkg": "rxode2", "_universes": [ "nlmixr2", "mattfidler" ], "_previous": "5.1.4.9000", "_progress_url": "https://github.com/r-universe/nlmixr2/actions/runs/30122800939", "_binaries": [ { "r": "4.7.0", "os": "win", "version": "5.1.4", "date": "2026-07-20T13:52:28.000Z", "arch": "x86_64", "commit": "f28adb4930bbd5fcdf29b9148d5118bf332d128f", "fileid": "https://r2.ropensci.org/f060195a183243a84ec9390b357a7b925167681e3c0ac75936213493bc8224db", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/29746807829" }, { "r": "4.5.3", "os": "win", "version": "5.1.4", "date": "2026-07-20T13:51:04.000Z", "arch": "x86_64", "commit": "f28adb4930bbd5fcdf29b9148d5118bf332d128f", "fileid": "https://r2.ropensci.org/6d66d6afc187643fbafbab908678378c24c5a2f4daa53570ba43c3bd51282b8e", "status": "success", "check": "NOTE", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/29746807829" }, { "r": "4.6.1", "os": "win", "version": "5.1.4", "date": "2026-07-20T13:51:00.000Z", "arch": "x86_64", "commit": "f28adb4930bbd5fcdf29b9148d5118bf332d128f", "fileid": "https://r2.ropensci.org/3d6e10e9ccafeddce97cb53d8cc46f1a9423787fa0d45df0eb97c5e934dab55b", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/29746807829" }, { "r": "4.7.0", "os": "linux", "version": "5.1.5", "date": "2026-07-24T12:06:32.000Z", "distro": "resolute", "arch": "aarch64", "commit": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "fileid": "https://r2.ropensci.org/50007fb441e9cb87135a2253d8ce69a5529a364fc35098ab1decf1a875087059", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288" }, { "r": "4.7.0", "os": "linux", "version": "5.1.5", "date": "2026-07-24T12:06:19.000Z", "distro": "resolute", "arch": "x86_64", "commit": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "fileid": "https://r2.ropensci.org/81047be8c9ad5f74f5a32c0de6b76b12f6524a84d4c1d65f7245faa41663c0fe", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288" }, { "r": "4.6.1", "os": "linux", "version": "5.1.5", "date": "2026-07-24T12:06:24.000Z", "distro": "resolute", "arch": "aarch64", "commit": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "fileid": "https://r2.ropensci.org/1e8eba7ab6a83d51d42661af1787c2c22e6a321b8b24833e643ebb4743524816", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288" }, { "r": "4.6.1", "os": "linux", "version": "5.1.5", "date": "2026-07-24T12:06:35.000Z", "distro": "resolute", "arch": "x86_64", "commit": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "fileid": "https://r2.ropensci.org/eaf026439d408daf8fb1f82356367b64e319f45ae52d587649ce501626ae3d0f", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288" }, { "r": "4.5.3", "os": "mac", "version": "5.1.5", "date": "2026-07-24T12:05:25.000Z", "arch": "aarch64", "commit": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "fileid": "https://r2.ropensci.org/2ad92e1d5d53da2cd30b384f6751b2578c7b31c3505f85bbb5d63ed88b8abaec", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288" }, { "r": "4.5.3", "os": "mac", "version": "5.1.5", "date": "2026-07-24T12:11:29.000Z", "arch": "x86_64", "commit": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "fileid": "https://r2.ropensci.org/89f93de3dd95f71a94b3516787034c5957a85e2909b5a9350d480d33f9875e8d", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288" }, { "r": "4.6.1", "os": "mac", "version": "5.1.5", "date": "2026-07-24T12:05:54.000Z", "arch": "aarch64", "commit": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "fileid": "https://r2.ropensci.org/1de95598a78b81e22cf3158dbfd9acf3e251dfa7ef5dbfa3147a3101be2f024b", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288" }, { "r": "4.6.1", "os": "mac", "version": "5.1.5", "date": "2026-07-24T12:08:38.000Z", "arch": "x86_64", "commit": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "fileid": "https://r2.ropensci.org/573bf8f9aa2d86a05eab329353e991b2bea0370a3dbf7323173cf5df6a92cf17", "status": "failure", "check": "ERROR", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288" }, { "r": "4.6.0", "os": "wasm", "version": "5.1.5", "date": "2026-07-24T12:06:41.000Z", "arch": "emscripten", "commit": "9bb660ea9128817aec63cf7d103d8d655e31a6cd", "fileid": "https://r2.ropensci.org/c5501f567b575250f546aca621e5b878270af6bb8285c5c11ec0fa85d095b05b", "status": "success", "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/30090813288" } ] }