{
  "_id": "6a1829ddacfb0bcc41db56c0",
  "Package": "monolix2rx",
  "Title": "Converts 'Monolix' Models to 'rxode2'",
  "Version": "0.0.6",
  "Authors@R": "c(person(\"Matthew\",\"Fidler\", role = c(\"aut\", \"cre\"), email = \"matthew.fidler@gmail.com\", comment=c(ORCID=\"0000-0001-8538-6691\")),\nperson(\"Justin\", \"Wilkins\", role = \"ctb\", email = \"justin.wilkins@occams.com\", comment=c(ORCID=\"0000-0002-7099-9396\")))",
  "Description": "'Monolix' is a tool for running mixed effects model using\n'saem'. This tool allows you to convert 'Monolix' models to\n'rxode2' (Wang, Hallow and James (2016)\n<doi:10.1002/psp4.12052>) using the form compatible with\n'nlmixr2' (Fidler et al (2019) <doi:10.1002/psp4.12445>). If\navailable, the 'rxode2' model will read in the 'Monolix' data\nand compare the simulation for the population model individual\nmodel and residual model to immediately show how well the\ntranslation is performing. This saves the model development\ntime for people who are creating an 'rxode2' model manually.\nAdditionally, this package reads in all the information to\nallow simulation with uncertainty (that is the number of\nobservations, the number of subjects, and the covariance\nmatrix) with a 'rxode2' model.  This is complementary to the\n'babelmixr2' package that translates 'nlmixr2' models to\n'Monolix' and can convert the objects converted from\n'monolix2rx' to a full 'nlmixr2' fit. While not required, you\ncan get/install the 'lixoftConnectors' package in the 'Monolix'\ninstallation, as described at the following url\n<https://monolixsuite.slp-software.com/r-functions/2024R1/installation-and-initialization>.\nWhen 'lixoftConnectors' is available, 'Monolix' can be used to\nload its model library instead manually setting up text files\n(which only works with old versions of 'Monolix').",
  "License": "MIT + file LICENSE",
  "URL": "https://nlmixr2.github.io/monolix2rx/,\nhttps://github.com/nlmixr2/monolix2rx/",
  "Encoding": "UTF-8",
  "Roxygen": "list(markdown = TRUE)",
  "RoxygenNote": "7.3.2",
  "Config/testthat/edition": "3",
  "Config/Needs/website": "rmarkdown",
  "Config/pak/sysreqs": "libfontconfig1-dev libfreetype6-dev make libicu-dev",
  "Repository": "https://nlmixr2.r-universe.dev",
  "Date/Publication": "2026-05-02 19:22:25 UTC",
  "RemoteUrl": "https://github.com/nlmixr2/monolix2rx",
  "RemoteRef": "HEAD",
  "RemoteSha": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
  "NeedsCompilation": "yes",
  "Packaged": {
    "Date": "2026-05-28 11:33:04 UTC",
    "User": "root"
  },
  "Author": "Matthew Fidler [aut, cre] (ORCID:\n<https://orcid.org/0000-0001-8538-6691>),\nJustin Wilkins [ctb] (ORCID: <https://orcid.org/0000-0002-7099-9396>)",
  "Maintainer": "Matthew Fidler <matthew.fidler@gmail.com>",
  "MD5sum": "533bb9e3ed9cc4338ef787f28d9769ae",
  "_user": "nlmixr2",
  "_type": "src",
  "_file": "monolix2rx_0.0.6.tar.gz",
  "_fileid": "3c31061cecad003aaa67b656fe29030f966e04d0a7e010eacaa03582bf0dd2be",
  "_filesize": 901407,
  "_sha256": "3c31061cecad003aaa67b656fe29030f966e04d0a7e010eacaa03582bf0dd2be",
  "_created": "2026-05-28T11:33:04.000Z",
  "_published": "2026-05-28T11:41:17.563Z",
  "_distro": "noble",
  "_jobs": [
    {
      "job": 78281731743,
      "time": 269,
      "config": "linux-devel-arm64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "7264843115"
    },
    {
      "job": 78281731622,
      "time": 265,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "7264841486"
    },
    {
      "job": 78281731910,
      "time": 243,
      "config": "linux-release-arm64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7264834885"
    },
    {
      "job": 78281731733,
      "time": 259,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7264839661"
    },
    {
      "job": 78281731883,
      "time": 152,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "7264806432"
    },
    {
      "job": 78281731731,
      "time": 444,
      "config": "macos-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "7264898954"
    },
    {
      "job": 78281731786,
      "time": 323,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7264860287"
    },
    {
      "job": 78281731656,
      "time": 296,
      "config": "macos-release-x86_64",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7264851450"
    },
    {
      "job": 78280993627,
      "time": 284,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7264756877"
    },
    {
      "job": 78281731600,
      "time": 178,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7264814160"
    },
    {
      "job": 78281731792,
      "time": 245,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "7264835163"
    },
    {
      "job": 78281731815,
      "time": 237,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "7264832798"
    },
    {
      "job": 78281731666,
      "time": 232,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7264831300"
    }
  ],
  "_buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/nlmixr2/monolix2rx",
  "_commit": {
    "id": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
    "author": "Bill Denney <billdenney@users.noreply.github.com>",
    "committer": "GitHub <noreply@github.com>",
    "message": "Merge pull request #37 from nlmixr2/fix/snapshot-updates\n\nUpdate vdiffr snapshots for R 4.6 / ggplot2 4.0 rendering",
    "time": 1777749745
  },
  "_maintainer": {
    "name": "Matthew Fidler",
    "email": "matthew.fidler@gmail.com",
    "login": "mattfidler",
    "description": "Also a Novartis employee;  Can reach me at my Novartis email: matt.fidler@novartis.com",
    "uuid": 514778,
    "orcid": "0000-0001-8538-6691"
  },
  "_registered": true,
  "_dependencies": [
    {
      "package": "dparser",
      "role": "LinkingTo"
    },
    {
      "package": "rxode2",
      "role": "LinkingTo"
    },
    {
      "package": "Rcpp",
      "role": "LinkingTo"
    },
    {
      "package": "Rcpp",
      "role": "Imports"
    },
    {
      "package": "checkmate",
      "role": "Imports"
    },
    {
      "package": "cli",
      "role": "Imports"
    },
    {
      "package": "dparser",
      "role": "Imports"
    },
    {
      "package": "withr",
      "role": "Imports"
    },
    {
      "package": "ggplot2",
      "role": "Imports"
    },
    {
      "package": "ggforce",
      "role": "Imports"
    },
    {
      "package": "stringi",
      "role": "Imports"
    },
    {
      "package": "crayon",
      "role": "Imports"
    },
    {
      "package": "lotri",
      "role": "Imports"
    },
    {
      "package": "magrittr",
      "role": "Imports"
    },
    {
      "package": "rxode2",
      "version": ">= 3.0.4",
      "role": "Imports"
    },
    {
      "package": "devtools",
      "role": "Suggests"
    },
    {
      "package": "testthat",
      "version": ">= 3.0.0",
      "role": "Suggests"
    },
    {
      "package": "xgxr",
      "role": "Suggests"
    },
    {
      "package": "vdiffr",
      "role": "Suggests"
    }
  ],
  "_owner": "nlmixr2",
  "_selfowned": true,
  "_usedby": 1,
  "_updates": [
    {
      "week": "2025-28",
      "n": 3
    },
    {
      "week": "2025-29",
      "n": 5
    },
    {
      "week": "2025-35",
      "n": 1
    },
    {
      "week": "2026-18",
      "n": 1
    }
  ],
  "_tags": [
    {
      "name": "v0.0.5",
      "date": "2025-07-15"
    },
    {
      "name": "v0.0.6",
      "date": "2025-08-29"
    }
  ],
  "_topics": [
    "monolix",
    "nlmixr2",
    "pharmacometrics",
    "rxode2",
    "cpp"
  ],
  "_stars": 1,
  "_contributors": [
    {
      "user": "mattfidler",
      "count": 408,
      "uuid": 514778
    },
    {
      "user": "billdenney",
      "count": 2,
      "uuid": 10359931
    }
  ],
  "_userbio": {
    "uuid": 94710774,
    "type": "organization",
    "name": "nlmixr2"
  },
  "_downloads": {
    "count": 365,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/monolix2rx"
  },
  "_devurl": "https://github.com/nlmixr2/monolix2rx",
  "_pkgdown": "https://nlmixr2.github.io/monolix2rx/",
  "_searchresults": 19,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/monolix2rx.html",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_homeurl": "https://github.com/nlmixr2/monolix2rx",
  "_realowner": "nlmixr2",
  "_cranurl": true,
  "_releases": [
    {
      "version": "0.0.1",
      "date": "2024-09-20"
    },
    {
      "version": "0.0.2",
      "date": "2024-09-20"
    },
    {
      "version": "0.0.3",
      "date": "2024-10-24"
    },
    {
      "version": "0.0.4",
      "date": "2024-11-28"
    },
    {
      "version": "0.0.5",
      "date": "2025-07-15"
    },
    {
      "version": "0.0.6",
      "date": "2025-08-29"
    }
  ],
  "_exports": [
    ".getNbdoses",
    ".getStiff",
    ".monolixGetMlxtran",
    "%>%",
    "autoplot",
    "expit",
    "ini",
    "logit",
    "lotri",
    "mlxtran",
    "mlxTxt",
    "model",
    "model<-",
    "monolix2rx",
    "rxode",
    "RxODE",
    "rxode2",
    "rxRename",
    "rxSolve",
    "rxUiGet"
  ],
  "_help": [
    {
      "page": "mlxtran",
      "title": "Read and parse mlxtran lines",
      "topics": [
        "mlxtran"
      ]
    },
    {
      "page": "mlxTxt",
      "title": "Get equation block from a Monolix model txt file",
      "topics": [
        "mlxTxt"
      ]
    },
    {
      "page": "monolix2rx",
      "title": "Translate a monolix file to rxode2",
      "topics": [
        "monolix2rx"
      ]
    }
  ],
  "_pkglogo": "https://github.com/nlmixr2/monolix2rx/raw/HEAD/man/figures/logo.png",
  "_readme": "https://github.com/nlmixr2/monolix2rx/raw/HEAD/README.md",
  "_rundeps": [
    "armadillo4r",
    "backports",
    "base64enc",
    "BH",
    "cachem",
    "checkmate",
    "cli",
    "cpp11",
    "cpp4r",
    "crayon",
    "data.table",
    "desc",
    "digest",
    "dparser",
    "farver",
    "fastmap",
    "ggforce",
    "ggplot2",
    "glue",
    "gtable",
    "inline",
    "isoband",
    "jsonlite",
    "labeling",
    "lifecycle",
    "lotri",
    "magrittr",
    "MASS",
    "memoise",
    "polyclip",
    "PreciseSums",
    "qs2",
    "R6",
    "RColorBrewer",
    "Rcpp",
    "RcppArmadillo",
    "RcppEigen",
    "RcppParallel",
    "rex",
    "rlang",
    "rxode2",
    "rxode2ll",
    "S7",
    "scales",
    "sitmo",
    "StanHeaders",
    "stringfish",
    "stringi",
    "sys",
    "systemfonts",
    "tidyselect",
    "tweenr",
    "vctrs",
    "viridisLite",
    "withr"
  ],
  "_sysdeps": [
    {
      "shlib": "libstdc++",
      "package": "libstdc++6",
      "source": "gcc",
      "version": "14.2.0-4ubuntu2~24.04.1",
      "name": "c++",
      "homepage": "http://gcc.gnu.org/",
      "description": "GNU Standard C++ Library v3"
    }
  ],
  "_score": 4.056904851336473,
  "_indexed": true,
  "_nocasepkg": "monolix2rx",
  "_universes": [
    "nlmixr2",
    "mattfidler"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.0.6",
      "date": "2026-05-28T11:36:47.000Z",
      "distro": "noble",
      "arch": "aarch64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "6ab84eca624de8e1b3241ccac0b7dca3b41c6191baa4b3c90699f4d7b68dd2f2",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.0.6",
      "date": "2026-05-28T11:36:30.000Z",
      "distro": "noble",
      "arch": "x86_64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "6bf6b5d8bbf7c4ed1833372a136d36b65987298831cd474b8c460a90a290ebeb",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "0.0.6",
      "date": "2026-05-28T11:36:23.000Z",
      "distro": "noble",
      "arch": "aarch64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "524869e8490c1783c825f615ba3bc3267a7934758c07d90f5ccca13a50d3afcc",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "0.0.6",
      "date": "2026-05-28T11:36:27.000Z",
      "distro": "noble",
      "arch": "x86_64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "9930e10a8f81af2a0d354ca58b731a1b64bdb1ba24e08107f2fedadd1330c5bf",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.0.6",
      "date": "2026-05-28T11:35:07.000Z",
      "arch": "aarch64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "c29ede4843b321724560fe2cd72fe27f78c9681578c7b5ba7d5fca5c0b6b9ead",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.0.6",
      "date": "2026-05-28T11:37:41.000Z",
      "arch": "x86_64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "96f70df824350466c0efc3e5d1c93304196f508140886fcb624fd462ea851f4c",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "0.0.6",
      "date": "2026-05-28T11:36:33.000Z",
      "arch": "aarch64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "f02fa72d4c0fd389c5bf599e58cdf482dfd50f583224f0fdb37f6d7716ddc871",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "0.0.6",
      "date": "2026-05-28T11:36:30.000Z",
      "arch": "x86_64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "e619313942e084a93e48da1dfe2abd580fa4fbb0deb979405f88ffd45e7e371c",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "0.0.6",
      "date": "2026-05-28T11:36:24.000Z",
      "arch": "emscripten",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "ce905fb142fd9a55e60c756c36f4384491ef4940d967a88fdbcfef25296900a0",
      "status": "success",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "0.0.6",
      "date": "2026-05-28T11:35:14.000Z",
      "arch": "x86_64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "f6d93fcaecac381e12843ad2b8472e53c74b5d175e99752c7a757b98ee3496ee",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "0.0.6",
      "date": "2026-05-28T11:34:56.000Z",
      "arch": "x86_64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "2ee8b90ad8fc8093d83cfd74e649ad1078e9d1c34d9928a25ffc777415ef4e7c",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "0.0.6",
      "date": "2026-05-28T11:35:02.000Z",
      "arch": "x86_64",
      "commit": "ca1ffea087e2a48ffbafe9e758e59bf7f8efa59a",
      "fileid": "592ed60148e8438371c454b3ddf0f6018a6f77f5e4e3e97d70b9f3abf776735b",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/nlmixr2/actions/runs/26571907865"
    }
  ]
}